Genus Capripoxvirus

Question 1

3 diseases under this genus

Answer 1

-sheep pox
-goat pox
-lumpy skin disease in cattle

Question 2

sheeppox and goatpox distribution

Answer 2

endemic in africa, asia and some areas of europe

Question 3

sheepox and goatpox - same or diff virus and are they distinguishable on serology?
-notifiable??

Answer 3

different viruses but serologically indistinguishable
NOTIFIABLE
-systemic viruses!!

Question 4

Sheeppox and goat pox transmission

Answer 4

-highly contagious
-virus enters through respiratory tract and transmission is by aerosol route
-spread can occur through mucous membrane or abraded skin, especially if in direct contact with contaminated iatrogenic materials
-virus present in nasal and oral secretions for weeks after infection
-virus can survive in dry scab for months
-evidence for mechanical transmission by biting arthropods

AEROSOL is most common route

Question 5

sheeppox pathogenesis

Answer 5

SYSTEMIC DISEASE
-incubation period followed by leukocyte associated viremia - virus is brought across body in leukocytes
-virus localizes in skin and other internal organs
-depositon of immune complexes results in severe necrotizing vasculitis develop in arterioles and postcap. venules of the skin (TYPE 3 HS) –> resulting in ischemic necrosis of dermis and epidermis

Question 6

sheeppox clinical signs (with 2 diff. forms)

Answer 6

malignant: seen in lambs and nonnative breeds EX: merino, pox lesions on skin, GIT, UT, internal organs, respiratory tract, vagina, secondary pneumonia is common, cutaneous nodules all over the body, lesions heal leaving a star shaped scar, free of hair or wool

-HIGH MORTALITIY AND HIGH CASE FATALITY RATE

benign form: more common in adults and resistant breeds, only skin lesions occur, very mild or none systemic reaction

Question 7

sheeppox prevention and control

Answer 7

NOTIFIABLE DISEASE
-VAX: subunit vax, killed vax elicit temporary protection, live attenuated vax is better protection

Question 8

goatpox
-areas where its found
-clin signs similar to ?
-what age group suffers and waht type of disease is this

Answer 8

-Africa, asia, europe
-REPORTABLE DX
-clinically similar to sheeppox
-young kids suffer systemic diseases, milder form of disease in adults

Question 9

lumpy skin disease
-where is it found
-transmission
-host
-clinical findings

Answer 9

africa, middle east
-arthropod vector (most common) and direct contact
-CATTLE
-fever, multiple nodular lesions on skin and mucous membrane, lymphadenopathy