Genus Avipoxvirus

Question 1

what virus is within the genus

Answer 1

fowlpox

Question 2

first virus to be… ?
-hosts
-distribution

Answer 2

grown in embryonated eggs
hosts: poultry and turkey
worldwide

Question 3

transmission

Answer 3

virus resistant to desiccation, survive in exfoliated scabs for long periods of time, transmitted within a flock through minor wounds and abrasions in mouth, comb, wattles, skin, mechanically by lice, mosquitos and ticks, maybe by aerosol route

Question 4

3 forms of the disease

Answer 4

1. cutaneous (dry form)
2. diphtheritic form (wet form)
3. ocular form

Question 5

cutaneous form (dry form) CS

Answer 5

-most common
-low mortality
-results from biting arthropods, or mechanical transmission to injured skin
-small papules on comb, wattles, around beak
-lesions develop on legs, feet
-nodules become yellowish and progress to a thick scab
-sharp fall in egg prod.
-uncomplicated cases: affected birds recover in 4 weeks
-VERY CONTAGIOUS

Question 6

diphtheritic form (wet form) CS

Answer 6

-probably caused by droplet infection
-involves infection of mucous membranes of mouth, pharynx, larynx, trachea
-lesions result in necrotic pseudomembranes which cause death by asphyxiation
POOR PROGNOSIS

Question 7

ocular form CS

Answer 7

conjunctivitis, cheesy exudate accumulates under eye lids and can cause temporary blindness

Question 8

avipoxvirus characteristic inclusion bodies (2)

Answer 8

1. bollinger bodies: eosinophilic granular intracytoplasmic
2. borrel bodies: occur inside bollinger bodies, spherical bodies obtained by tryptic digestion of bollinger bodies

Question 9

fowlpox virus vax and control

Answer 9

VAX: modified live fowlpox or pigeon pox virus vaccines of chicken embryo or avian cell culture origin
-recombinant fowlpox vectored vax have been developed

-control: mosquitos and other biting insects