Genetics Unit Quiz Flashcards

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1
Q

Distinguish mitosis and meiosis.

A

Mitosis is asexual reproduction, is when offspring are produced by 1 parent through binary fission, therefore it is genetically identical

Meiosis is sexual reproduction and is also referred to as reduction division. It occurs in the germ cells of the gonads. Daughter cells contain half the chromosomes as parent cells (23)

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2
Q

Distinguish between a gene and allele.

A

A gene is the instructions for each trait found in chromosomes, they are arranged in a specific order on each chromosome

A allele is a singular trait of a gene that controls each trait.

Ex. Floppy ears in dogs is controlled by a gene that has two possible forms (alleles)
B bent ears
b erect ears

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3
Q

Distinguish dominent and recessive.

A

A dominent allele is the expressed allele, it is represented with a capital letter.

A masked allele is called recessive.

The dominent allele will be the trait that is expressed if a gene is heterozygous.

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4
Q

Distinguash homozygous and heterozygous.

A

Homozygous is when both alleles are the same. It can be homozygous recessive or homozygous dominent.

Heterozygous is when the two alleles are different and the dominent allele is expressed.

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5
Q

Distinguish phenotype and genotype.

A

Genotypes are different allele combinations.
Phenotypes is the trait that is expressed.

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6
Q

Distinguish between Somatic cell and sex cells.

A

Somatic cells have a diploid number of chromosomes, which is 46 chromosomes, while sex cells have a haploid number of chromosomes, which is a total of 23 chromosomes.

Somatic cells are all body cells besides sex cells.

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7
Q

Distinguish autosomes and sex chromosomes.

A

Autosomes are the first 44 chromosomes in humans. Sex chromosomes are the last 2 chromosomes that determine the gender of humans.

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8
Q

Distinguish between DNA and RNA.

A

DNA is double stranded and stays in the nucleus DNA is formed from deoxyribose. RNA is a transcription of DNA that is composed of ribose.

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9
Q

Distinguish between nucleotide and amino acid.

A

A nucleotide is made out of sugar, nitrogen base and phosphate and is the base nucleic acids (DNA) (RNA).
Amino acids compose protein, different amino acid formations determine types of proteins.

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10
Q

Distinguish between Transcription and translation.

A

Transcription takes place in the nucleus. It is used to make DNA into RNA. At the end of transcription the RNA exits the nucleus and goes into the cytoplasm and translation stage where amino acids are used to from a sequence and proteins are formed.

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11
Q

Distinguish a codon and anticodon.

A

A codon is a three-nucleotide or triplet sequence found on mRNA that codes for a certain amino acid during translation. The anticodon is a three-nucleotide sequence found on tRNA that binds to the corresponding mRNA sequence. The amino acid transported by the tRNA molecule is determined by the anticodon sequence.

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12
Q

Why is meiosis referred to as reduction division. What event is responsible for reducing chromosome number. How many daughter cells are formed?

A

It is referred to reduction division due to its result of 23 chromosomes for each of the 4 daughter cells in the final stage. Meiosis 1 is responsible for reducing chromosome number. 4 daughter cells are formed.

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13
Q

List Mendels three laws.

A

-Law of dominance
-law of segregation (hom/het)
-law of independent assortment (foil)

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14
Q

What is the term crossing over and what effects does it have on genetic variation.

A

Crossing over occurs in meiosis 1 when chromosome homologous pairs intertwine, break and exchange genetic info which results in more genetic variation.

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15
Q

Look at pedigree

A

.

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16
Q

Look at DNA molecule

A
17
Q

What is the purpose of DNA replication. What are the four steps, why is it semi conservative.

A

DNA replication is vital in preserving and transmitting traits. It is done during interphase of the cell cycle. It is essential for cell growth and repair.
Step 1: DNA uncoils

Step 2: DNA unzips creating two parent strands (hydrogen bonds are broken by helicase enzyme)

Step3: DNA molecule rebuilds and DNA polymerase attaches free nucleotides to corresponding bases making two complete DNA molecules

Step 4: both molecules recoil allowing for mitosis and meiosis to begin

It is semi conservative because a parent strand of DNA is used as a template therefore gives less chance of error.

18
Q

What is the purpose of protein synthesis?

A

The purpose of protein synthesis is to make cells for the body. It uses DNA instructions to build certain proteins with certain functions.

19
Q

What are the three kinds of RNA?

A

mRNA: like the blueprint for protein construction. It goes into the nucleus and uses a strand of DNA to copy its own strand using free floating nucleotides. Thymine is replaced by uracil in RNA

rRNA: it is the construction site where protein is made. It is the big ball where the anti codons attach to codons on rna

tRNA: delivers the proper amino acids to the right site at the right time. It Carries the amino acid and drop it off which attach together by peptide bonds.

20
Q

Describe the relationship between DNA, RNA, chromosomes, and genes.

A

Chromosomes hold everything and are within the nucleus. Genes are made up of DNA, and RNA is a copy of the genes on the DNA.

21
Q

Differentiate between chromosomal and gene mutation. What are the biological results and causes of each.

A

Gene mutation is caused by portions of DNA being deleted, duplicated, inverted, or translocated. It only affects a small portion of chromosomes. Its results are not visible and usually result in a enzyme deficiency (lactose intolerant).

Chromosomal mutation is caused by
- non disjunction: failure of chromosomes to split during meiosis resulting in gametes having too many or too few chromosomes
-translocation or deleting of an arm of a chromosome
Because changes affect large portions of chromosomes the change is visible and organisms look different from the rest of the species. ( down syndrome)

22
Q

How are pedigree charts and karyotypes useful in diagnostic testing.

A

A karyotype is a micrograph picture taken of the chromosomes during prophase 1 of meiosis. They allow you to easily view too many chromosomes, or lack of chromosomes, along with mis formed.
Pedigrees allow you to view a inherited condition, along with seeing what risk people are at for certain things.

23
Q

What is transgenic manipulation?

A

Transgenic manipulation is when scientists manipulate plants and foods and add desired traits onto the chromosomes of them.

24
Q

What is cloning?

A

Cloning is when a somatic cell and a enucleated egg are both used to produce a genetically identical offspring as the somatic cell. It is controversial because it is considered the manufacture and destruction of a human life.

25
Q

What is pcr.

A

The polymerase chain reaction (PCR) is a method widely used to make millions to billions of copies of a specific DNA sample rapidly, allowing scientists to amplify a very small sample of DNA (or a part of it) sufficiently to enable detailed study.

26
Q

What is DNA fingerprinting

A

DNA fingerprinting is the process of finding a humans DNA based off of there fingerprints.

27
Q

What is eugenics?

A

Increasing inheritable genetics to give to offspring. It is picking certain traits and altering DNA and chromosomes to alter the appearance of offspring. It is mutating babies to give the best traits. It is controversial because people disagree with it saying it opposes life and nature. Hitler and the nazis also believed in keeping only the “perfect people” and killing all people who aren’t what they viewed as perfect.

28
Q

What are the chromosome laws?

A

-genes are located in chromosomes
-chromosomes come in pairs
-chromosomes sort independently
-chromosomes determine traits
-chromosomes segregate

29
Q

What are the four nitrogene bases and which combine to which?

A

Guanine, cytosine, thymine, adenine
GUANINE triple bond to CYTOSINE
THYMINE double bond to ADENINE

In RNA Uracil replaces Thymine

30
Q

What are the chromosomal disjunction disorders?

A

A) Down syndrome (extra chromosome 21) trisomy 21
-diminished mental capacity
B) Turner syndrome (missing a x chromosome) x
-females that don’t develop
C) Klinefelter (extra X chromosome) XXy
-sterile
-males who possess female traits
D) trisomy x (47 chromosomes) XXX
-mental impairment
E) trisomy Y (47 chromosomes) XYY
-super males

31
Q

What are the genetic mutations and what do they cause?

A

Deletion and Insertion of nucleotides is a frame shift which shifts all following sequences

If substitution changes amino acid it is called a missense mutation

If substitution does not change amino acid it is a silent mutation

If substitution changes to a stop codon it is a nonsense mutation