Genetics Flashcards
Mendelian Genetics
complete dominance - dominant alleles completely mask recessive allele
- 2 alleles determine one trait
- 2 recessive alleles express recessive trait
- most human traits are not Mendelian
allele expression
Allele expression not always complete dominance where the dominant alleles override recessive ones • Alleles of a single gene may interact together & create unexpected phenotypes • This could be caused by: • Sex-linked traits • Incomplete dominance • Codominance • Multiple alleles
Incomplete Dominance
Neither allele dominates and the heterozygote is an intermediate phenotype • Examples color in snapdragons: white & red alleles make pink
Codominance
Both alleles are independently and equally
expressed in the heterozygote
• Examples:
• Roan (stippled red & white) coat color in cattle
• ABO human blood groups
Multiple Alleles in Blood
Humans have 4 blood group phenotypes: A, B, AB & O • The four common blood groups of the human ABO blood group system are determined by three alleles: IA, IB, i • IA & IB are codominant & i is recessive
Pleiotropy
One gene impacts numerous different phenotypic characters • Example: albinism in which the mutation of one gene affects the production of melanin which has effects multiple traits in the individual
Epistasis
• One gene affects the phenotypic expression of
another gene
– Example in mice: one gene determines the color of fur (brown or black) & a separate gene determines if
pigment will be deposited into the fur (color or albino)
Polygenic Inheritance
• Multiple genes may interact to create one phenotype creating a continuum in the
phenotype
– Aka: quantitative characters
– Environmental factors create the smooth bell curve
shape
Nature & Nurture
• The environment impacts phenotypic expression of genes creating a range of
phenotypes that depend on environmental conditions (aka: the norm of reaction)
– Some traits have an inflexible norm of range
(blood types) while other vary greatly (red
blood cells) based on the environment
– Polygenic traits tend to have the greatest
norms of reactions especially when
considering environmental impacts
Law of Independent Assortment
when two or more characteristics are inherited, individual hereditary factors assort independentlyduring gamete production, giving different traits an equal opportunity of occurring together
Law of segregation
During gamete formation, the alleles for each genesegregate from each other into separate gametes so that each gamete carries only one allele for each gene.