Genetics Flashcards

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1
Q

Mendelian Genetics

A

complete dominance - dominant alleles completely mask recessive allele

  • 2 alleles determine one trait
  • 2 recessive alleles express recessive trait
  • most human traits are not Mendelian
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2
Q

allele expression

A
Allele expression not always
complete dominance where
the dominant alleles
override recessive ones
• Alleles of a single gene may interact together & create unexpected phenotypes
• This could be caused by:
• Sex-linked traits
• Incomplete dominance
• Codominance
• Multiple alleles
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3
Q

Incomplete Dominance

A
Neither allele dominates
and the heterozygote is
an intermediate phenotype
• Examples color in
snapdragons: white &
red alleles make pink
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4
Q

Codominance

A

Both alleles are independently and equally
expressed in the heterozygote
• Examples:
• Roan (stippled red & white) coat color in cattle
• ABO human blood groups

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5
Q

Multiple Alleles in Blood

A
Humans have 4 blood
group phenotypes: A, B, AB
& O
• The four common blood
groups of the human ABO
blood group system are
determined by three alleles: IA, IB, i
• IA & IB are codominant & i
is recessive
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6
Q

Pleiotropy

A
One gene impacts numerous different phenotypic characters
• Example: albinism in which
the mutation of one gene
affects the production of
melanin which has effects
multiple traits in the
individual
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7
Q

Epistasis

A

• One gene affects the phenotypic expression of
another gene
– Example in mice: one gene determines the color of fur (brown or black) & a separate gene determines if
pigment will be deposited into the fur (color or albino)

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8
Q

Polygenic Inheritance

A

• Multiple genes may interact to create one phenotype creating a continuum in the
phenotype
– Aka: quantitative characters
– Environmental factors create the smooth bell curve
shape

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9
Q

Nature & Nurture

A

• The environment impacts phenotypic expression of genes creating a range of
phenotypes that depend on environmental conditions (aka: the norm of reaction)
– Some traits have an inflexible norm of range
(blood types) while other vary greatly (red
blood cells) based on the environment
– Polygenic traits tend to have the greatest
norms of reactions especially when
considering environmental impacts

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10
Q

Law of Independent Assortment

A

when two or more characteristics are inherited, individual hereditary factors assort independentlyduring gamete production, giving different traits an equal opportunity of occurring together

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11
Q

Law of segregation

A

During gamete formation, the alleles for each genesegregate from each other into separate gametes so that each gamete carries only one allele for each gene.

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