Genetics Flashcards

1
Q

Does meiosis or mitosis have PMAT I and PMAT II

A

Meiosis

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2
Q

Does a cell go back into G1 phase in meiosis like it does in mitosis?

A

No, the cycle ends at telophase II.

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3
Q

What are homologous chromosomes?

A

Same genes, same order but different alleles (comes from different parents)

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4
Q

What is the goal of meiosis I?

A

To separate homologous pairs

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5
Q

What is synapsis in prophase I?

A

Pairing up of homologous chromosomes

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6
Q

What are the two thing that happen in meiosis I that does not in mitosis?

A

1) synapsis - pairing of homologous chromosomes

2) crossing over - DNA exchange

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7
Q

What happens in metaphase I?

A

The tetrads are aligned at cell center

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8
Q

What are tetrads?

A

Four chromosomes (2 homologous pairs that have sister chromatids attached to each of them)

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9
Q

What happens in anaphase I?

A

1) Pull homologous pairs apart into different poles

2) Start cytokinesis

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10
Q

What happens in telophase I?

A

1) Reverse mitotic prophase (eggs do it but not sperm)

2) Finish cytokinesis

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11
Q

Which part (I or II) of meiosis the same as mitosis?

A

Meiosis II

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12
Q

What is nondisjunction?

A

The failure to properly separate DNA during gamete formation (meiosis)

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13
Q

How can you tell a nondisjunction in anaphase I vs anaphase II

A

Anaphase I failure would lead to four abnormal cells at the end

Anaphase II failure would lead to two abnormal cells at the end

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14
Q

What is a trait that comes with many forms (hair color)?

A

Polymorphic trait

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15
Q

What is a version of a gene?

A

Allele

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16
Q

What is a trait determined by many genes (height)?

A

Polygenic trait

17
Q

What is classical dominance (genetics)?

A

When one allele is dominant and another one is silent.

18
Q

What is incomplete dominance (genetics)?

A

When a new phenotype is seen by a heterozygous due to both the dominant and recessive allele playing a role.

Eg: flower colors (pink flower from red and white)

19
Q

What is codominance (genetics)?

A

When the two traits are both seen in the phenotype at the same time.

Eg: blood type (A, B or AB)

20
Q

What is epistasis?

A

Dominance between different genes and not between different alleles of the same gene.

Eg: albino gene prevents the expression of pigment genes. Albinos have the pigment gene, it is just suppressed.

21
Q

Is Rh factor an example of classical dominance?

A

Yes it is.

Eg: IaiRr = type A+, iiRR = type O+

22
Q

What is transfusion reactions?

A

The immune system reacting to foreign proteins due to the wrong type of blood type being transfused to a person.

23
Q

What is the universal donor?

24
Q

What is the universal recipient?

25
What is the law of independent assortment?
How one pair of alleles separates is independent of how other pairs separate
26
What are linked genes?
Genes found very close together on the same chromosome that might not sort independently.
27
Which generation can you tell gene linkage from?
F2 generation
28
What is 9:3:3:1 ratio (genetics)?
Classic expected unlinked ratio when a dihybrid is crossed. (BbSs with BbSs) If the ratio is off, then the genes are linked.
29
What is the expected unlinked ratio when BbSs is mixed with bbss?
1:1:1:1
30
What is the equation of recombination frequency?
(# of recombinants / total # of offspring) * 100
31
What is 12.5% of recombination frequency translate to in map units?
12.5 map units It means the genes are 12.5 map units away from each other. It's small so the genes are close to each other.
32
More recombination on a chromosome when?
The genes are further apart
33
What is the hardy-weinberg allele frequency equation?
p+q=1
34
What is the hardy-weinberg genotype frequency equation?
pp+2pq+qq=1
35
What are the 5 conditions for the hardy-weinberg to hold true?
1) No mutation 2) No natural selection 3) Total random mating 4) Large populations only 5) No migration