Genetics Flashcards
When only one dominant and one recessive allele exist for a given gene
complete dominance
When more than one dominant allele exists for a given gene
codominance
heterozygotes express phenotype intermediate between both parents
incomplete dominance
Proportion of the population that express phenotype
Penetrance
100% of indivi express phenotype that have allele
Full Penetrance
Some indivi express phenotype that have allele
high penetrance
Some indivi do not express phenotype that have allele
low penetrance
Different manisfestations of the same genotype across a population
expressivity
Point mutation
change in 1 nucleotide
point mutation that is silent
wobble
point mutation changes reading frame
Frame shift mutation
What are the two ways a frame shift mut can result?
Deletion and Addition
change in nucleotide results in change of a.a.
Missense
change in nucleotide introduces stop codon
Nonsense
A nonsense mutation results in what type of protein
Truncated
Mutations can be 3 typtes
Inversion, translocation, insertion
segment of gene jumps to another part of the gene
transposon
flow of genes between species
gene leakage
refers to changes in the composition of the gene pool due to chance
Genetic drift
small population is reproductively isolated
Founder Effect
castastrophic events can lead to ______ that reduce size of population
bottlenecks
mating between two genetically similar individuals
inbreeding
mating between two genetically similar individuals leads to reduced fitness
inbreeding depression
bring individuals of a diff population to an inbreeding population to create genetic diversity
outbreeding
encourages homozygosity which inc prevalence of both homo dom and rec genotypes
inbreeding
p+ q= 1
H.W
p^2+ 2pq+q^2= 1
H.W
p^2
freq homo dom
2pq
hetero
q^2
homo recessive
measure of organisms success in population; whether it survives, success in supporting offspring, and ability of the offspring to then support others
Inclusive fitness
Reproductive sucess
Fitness
Naturally occurring differences in form between members o the same population
polymorphisms
Fusion of gametes but lead to nonviable offspring
postzygotic mechanisms
reproductive isolation may prevent formation of zygote completely
prezygotic mechanisms
having one allele
hemizygous
Mendels first law
segregation
org has two alleles for each gene, which segregate during meiosis, resulting in gametes carrying only one allele for a trait.
Mendel’s second law
Independent assortment
inheritance for one allele does not influence the probability of inheriting a given allele for a different trait.
Why is genetic diversity good?
Inc probability of survival in changing environmental stresses
Genetic diversity is good for
fitness