Genetics Flashcards

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1
Q

What is meiosis?

A

Occurs in reproductive cells. Daughter cells have half the number of chromosomes. (E.g. 23 vs 46). The cell replicates itself and then splits the DNA to form 4 gametes.

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2
Q

What is a homozygous gene?

A

2 copies of a gene that are identical

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3
Q

What is a heterozygous gene?

A

2 copies of the same gene that are different.

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4
Q

What is an allele?

A

An alternative form of the same gene located on homologous chromosomes at identical locations.

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5
Q

What is a genotype and phenotype?

A

Genotype- the genetic makeup of an organism

Phenotype- the physical characteristics resulting from the genotype

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6
Q

What are dominant and recessive genes?

A

A dominant gene is a gene that is expressed in the phenotype. The recessive gene is a gene that is masked by the other gene

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7
Q

What are the components of the DNA structure?

A

Phosphate which is connected to deoxyribose sugar which is connected to the nitrogenous bases.

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8
Q

What are the 4 nitrogenous bases?

A

T- thymine
A- adenine
C- cytosine
G- guanine

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9
Q

What is a chromosomal abnormality?

A

A mutation that occurs in the chromosomes during meiosis and results in too many or too little chromosomes.

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10
Q

What is a gene abnormality?

A

When a mutation occurs in the DNA and the gene doesn’t code for the correct amino acid/protein

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11
Q

What are the three ways to alter a gene?

A

Adding a foreign gene, altering an existing gene or deleting a gene

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12
Q

What is adding a foreign gene and example?

A

A gene from another species is inserted into the organism so the GMO expresses the traits of that species (transgenic). E.g. Glow in the dark rabbits with a gene from a jellyfish.

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13
Q

What is altering an existing gene?

A

Making the gene express in a different way or at a higher level. E.g. Making growth hormones express more so the organism grows more.

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14
Q

What is deleting a gene? Example

A

Deactivating an existing gene to prevent the expression of that trait. E.g. Deactivation of tomato ripening gene for a longer shelf life.

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15
Q

What is mitosis?

A

Cell replication in all cells except reproductive cells. The cell replicates itself and then splits to form 2 identical cells.

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16
Q

Who were the 4 people who helped discover DNA structure?

A

Rosalind Franklin *
Maurice Wilkins *
James Watson ^
Francis Crick ^

17
Q

What did Franklin and Wilkins do?

A

They were crystallographers who took photos of DNA. Photograph 51 helped discover the DNA structure

18
Q

What did Watson and Crick do?

A

They used photograph 51 to determine that the structure of DNA was a double helix

19
Q

What did Gregor Mendel do?

A

He was a monk who did experiments cross breeding peas to determine patterns of inheritance and dominant and recessive genes.

20
Q

What happens in DNA replication?

A

The double helix unzips and nucleotides from the cytoplasm join to form 2 new double helixes

21
Q

What causes Down Syndrome?

A

It is a chromosomal abnormality that happens when meiosis doesn’t work properly and the 21st chromosome doesn’t split properly, causing someone to have 3 21 chromosomes

22
Q

What are arguments for GM?

A

Increase in food production- improves nutrition of people
Decrease in use of pesticides
Economic benefits

23
Q

What are arguments against GM?

A

Transgenic organisms spreading uncontrollably in the wild
Makes GM animals unhealthy
May cause resistance to pests or insects
Economic impacts/no benefits to farmers

24
Q

What is gene therapy?

A

Where the defective gene is replaced with a properly working gene

25
Q

What is the process of gene splicing?

A

Remove plasmid and cut it using enzyme
DNA is cut to isolate a gene
Join both to form gene
Implant gene inside bacteria to reproduce