Genes In Populations Flashcards

1
Q

Population genetics

A

Study of variation in allele and gene frequencies in populations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Gene pool

A

All of the alleles at every locus in a population

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Population

A

A group of individuals of the same species that live in the same area and interbreed, producing fertile offspring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Polymorphic

A

Occurring in several different forms, in particular w/ reference to species or genetic variation; more than one allele

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Monomorphic

A

Having or existing in only one form; only one allele

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Allele frequency

A

The proportion of a specific allele in a gene pool

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Genotype frequency

A

The proposition of individuals in a population w/ a specific genotype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Random mating

A

Mating w/ no regard to the genotype or phenotype of a mate, so that any sperm had an equal chance of fertilizing any egg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Hardy-Weinberg Equilibrium

A

State of a population in which frequencies of alleles and genotypes remain constant from generation to generation, provided that only Mendelian segregation and recombination of alleles are at work (I.e random mating and no evolution); p+q=1 and p^2+2pq+q^2=1

Describes the expected genetic makeup for a population that is not evolving at a particular locus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Null model

A

A model that gives expected outcomes if the thing you are interested in doesn’t happen; Ex: Hardy-Weinberg Equilibrium serves as an evolutionary null model

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

When are the conditions of HWE not met?

A

When the population is evolving or mating non randomly.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the four processes of evolution?

A

Selection, mutation, drift, migration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How many different gametes will be produced by an individual w/ the following genotype: AaBBCcDdee?

A

8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Individual organisms evolve. T or F?

A

False; populations evolve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Change in allele frequency over generations

A

Evolution at the scale of a population

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

In a gene pool, there are 20 B alleles and 80 b alleles. What is the b allele frequency?

A

80/100=0.8

17
Q

p and q

A

Represent the frequencies of two alleles at a locus; p+q=1; p is dominant allele and q is recessive allele

18
Q

At a locus w/ two alleles, p = 0.65. What is q?

A

1.00 - 0.65 = 0.35

19
Q

What do genotypes frequencies and alleles frequencies have to add up to?

A

1

20
Q

In a population of 320 red flowers, 20 white flowers, and 160 pink flowers, how many cW alleles are there?

A

2 x 20 = 40

160 + 40 = 200

21
Q

In a population of 320 red flowers, 20 white flowers, and 160 pink flowers, what is the cw allele frequency?

A

(320 + 20 + 160) x 2 = 1000

200/1000 = 0.2

22
Q

In a gene pool w/ the alleles A and a, where A allele frequency is 0.2, what is the expected frequency of AA genotypes (assuming random mating)?

A

0.2^2 = 0.04

23
Q

How many people are carriers of PKU alleles? PKU is a recessive disorder and it occurs in about 1 out of every 1000 babies born in the US.

A

q^2 = 0.0001
q = 0.01

p = 1- 0.01 = 0.99

frequency of carriers = 2 x 0.99 x 0.01 = 0.0198

Approx. 2% of the US population carry PKU alleles