General about vitamins Flashcards

1
Q

fat soluble vitamins

A
  • inductive; act on level of transcription
  • Vit. A, D, E, K, essential FA
  • can be stored except K
  • need transporter
  • no microbial synthesis, except vit. K
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2
Q

water soluble vitamins

A
  • act as co-factor
  • vit. B-group + C
  • no storage, except B12
  • microbial synthesis
    (- lipotropic agent (help catalyse the breakdown of fat during metabolism), choline, inositol)
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3
Q

deficiency/ too many terms

A

hypovitaminosis:
hypervitaminosis (fat soluble - storage)
aviaminosis - no vitamins

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4
Q

antivitamins

A

no time for vitamin uptake - leads to diarrhea, vomiting, other diseases

  • decr. microbial synthesis
  • bile, fat decr -> fat soluble vit. absorption decreases
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5
Q

vitamin antagoninsts

A

specific inhibitors of vitamins

  • competitive
  • degrader
  • unabsorbable complex formation
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6
Q

competitive inhibitor of vitamins

A

vit K - Dicoumarol, warfarin (anticoagulants)
vit B1 - pyrithymine
vit B9 - amethopterin (immunosupressent)

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7
Q

degrader of vitamins

A

thiaminase se. two rings: vitB1

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8
Q

unabsorbable vitamin complex

A

biotin(vit. H/B7) + avidine (egg white) -> no absorption

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9
Q

previtamins; some vits have a pre-form

A
B-carotene -> vit A
7-dehydrocholesterol -> vit D3
ergosterol -> vit D2
Trp -> nicotinic acid = niacin, B3
glucose -> ascorbic acid (not in hu, primates, guniae pig)
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10
Q

hypovitaminosis reasons

A

something off with:

  • feed
  • microbial synthesis
  • coprophagy is prevented
  • liver disease: storage, production, transport protein
  • vitamin receptor -> no cofactor formation/prodction
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