Gene Linkage Flashcards
What is gene linkage
The tendency of DNA sequences that are close together on a chromosome to be inherited together
Who tested the flies for gene linkage
T H Morgan
What did THMorgan test on gene linkage
Flies
What are the two types of mutations
Chromosomal and gene
What is chromosomal mutation
Change in the number or structure of chromosomes
What is gene mutation
Permanent alteration in DNA sequence
What has change in the number or structure of chromosomes
Chromosomal mutation
What has permanent alteration to DNA sequence
Gene mutation
What are the five kinds of Chromosomal mutations
Deletion Duplication Inversion Translocation Nondisjunction
What are the types of gene mutation
Point
Frame shift
Duplication
Cystic fibrosis
Inversion
Hemophilia a
Deletion
Some cancers, CMT
Translocation
Translocation Down’s syndrome
Nondisjunction
Down syndrome
Cystic fibrosis
Duplication
Hemophilia a
Inversion
Some cancers, CMT
Deletion
Translocation Down’s syndrome
Translocation
Down’s syndrome
Nondisjunction
Def of polyploidy
One too many chromosomes
One too many chromosomes
Polyploidy
Def of points mutation
Change in a single or a few neucleotide
Change in a single or a few neucleotide
Point mutation
Frameshift mutation
Number of nucleotides in a DNA sequence that is not divisible by three
Number of nucleotides in a DNA sequence that is not divisible by three
Frameshift mutation
Hypertrophic cardiomyopathy
Increase of muscle and heart disease