Gastroenteritis and Food Poisoning (FA) Flashcards
What is the incubation period of Campylobacter?
3-10 days
That is the mechanism of Campylobacter?
Inflammation of the colon
may spread to blood
How does Campylobacter spread?
Farm animals
What are the symptoms of Campylobacter?
Bloody diarrhoea
Abdominal pain
Self-liiting
How do you treat Campylobacter?
Usually none
How do you treat Campylobacter if there are co-morbidities or other indications?
(Macrolide) Erythromycin / Ciprofloxacin
What are the buzzwords for Campylobacter?
Bloody diarrhoea
Farm animals
Chicken
Poultry
What is the incubation ntiem of salmonella enteric?
12-48 hours
What is the mechanism of Salmonella enteric?
inflame ileum and colon
Mucosal damage
Decreased fluid absorption
What are the symptoms of Salmonella enteric?
Abdominal pain
Diarrhoea
Vomiting
Self-limiting
How do you treat Salmonella?
Ciprofloxacin
What are the buzzwords for Salmonella?
Farm animals
How do you type Salmonella?
According to the O-antigen
What are the symptoms of shigella?
Blood and pus in stool
Abdominal pain
Diarrhoea
How does Shigella sonni spread?
Human to human
What is the mechanism of Shigella sonni?
Mucosa inflammation
Self-limiting
What is the incubation period of Shigella?
1-9 days
What are the buzzwords for Shigella?
Children
Outbreak
Pus and blood in stool
Who gets E-coli?
Young children and elderly
What is the mechanism of E. coli?
Verotoxin binds to receptors on RBC and renal cells
Inhibit protein synthesis
Causes cell death
How does e. coli spread?
Cattle and infected water supplies
What are the symptoms of E. coli?
Abdominal pain
Bloody diarrhoea
HUS
What is HUS?
Haemolytic uraemia syndrome
How do you test for HUS?
Fever and blood test
How do you treat E. coli?
No treatment
What are the buzzwords for E. coli?
Cattle
HUS
Verotoxin
What causes typhoid/paratyphoid?
Salmonella typhi
Where is the body can be a chronic carrier of typhoon?
Gall bladder
Which distant sites are affected by tyhoiid?
Bone
What is the incubation time of typhoid?
2-3 weeks
What is the mechanism of typhoid?
Invades lumen
enter blood and lymphatic
Invade Peyer’s patches
How does typhoid spread?
Human spread only
What are the symptoms of typhoid?
Typhoid fever Rose spots Diarrhoea after 3 weeks Abdominal pain Rigor
How do you diagnose typhoid?
Stool test
Blood test
How do you treat typhoid?
Antibiotics-sensitivity test
Azithromycin
Vaccine available
What are the buzzwords for typhoid?
Travel
Fever
No diarrhoea
Rose spots
What is the shape of vibrio cholerae?
Comma bacillus
What is the mechanism of cholera?
Exotoxin
Out during of Is cells –> watery diarrhoea
What are the symptoms of cholera?
Rice water stool
How do you treat cholera?
Maintain electrolyte balance
What are the buzzwords for cholera?
War zone
Rice water diarrhoea
Is the incubation period for Staph aureus short of long?
Short
What his the mechanism of Staph aureus?
Enters stomach, vagus nerve and vomiting centre
What are the symptoms of Staph aureus?
Vomiting
What are the buzzwords for Staph aureus?
Vomiting
bakery
shrot onset
What kind of bacterium is Clostridium perfringes?
Gram negative
C. perfringes produces?
Spores
What is the mechanism of Clostridium perfringes?
Ingest spores
Spores survive cooking
What are the buzzwords for C. perfringes?
Meat
What kind of bacterium is C. diff?
Anaerobic gram positive
What are the 4 C’s of antibiotics that kill all other bacteria letting C. diff thrive?
Clindamyin
Co-amoxiclav
Cephalosporins
Ciprofloxacin
What are the risk factors for C. diff?
Immunocompromised
PPI
Recurrent CDI (Clostridium difficile infection)
How do you treat non severe C. diff?
Metronidazole PO 400mg tds (10 days)
How do you treat severe C. diff?
Vancomycin 125mg qds PO/NG (10 days)
+/- IV Metronidazole
What does Bacillus cereus produce?
Exotoxin
What kind of bacterium is bacillus cereus?
Gram positive aerobe
What is the mechanism of bacillus cereus?
Spores survive cooking
What are the buzzwords for B. cereus?
Reheated rice
What kind of parasite is Cryptosporidium?
Protozoa
What is Cryptosporidium associated with?
Animals and swimming pools
What is the mechanism of Cryptosporidium?
Cysts ingested, hatch and invade mucosa lining
Small bowel
What colour does Cryptosporidium have on microscopy?
Red
What are the symptoms of Cryptosporidium?
Worse in HIV
Self-limiting
What are the buzzwords for Cryptosporidium?
Swimming pools
Animal contact
Shit for britain
Giardia lambilia is an example of a?
Parasite
What is the mechansim of Giardia lambilia?
Cysts ingested
Invade upper GI
How does Giardia spread?
Contaminated water
What are the symptoms of Giardia?
Diarrhoea Malabsorption Anorexia Flatulence Fatty stool
How do you treat Giardia lambilia?
Metronidazole
What are the buzzwords for Giardia lambilia?
Water supply
Fatty stool
Anorexia
Happy face protozoa
What are enterobius vermicularis?
Thread worms
What is the mechanism of thread worms?
Eggs laid on perianus
Itched and ingested
What are the symptoms of threadworms?
Worms in stool
What are the buzzwords for Enterobius vermicularis (threadworms)?
Child
Itchy bum
What is the mechansim of Amoebiasis?
Amoebic cyst gobbles up red cels
Wich part of the body is affected by Amoebiasis?
Large bowel
Amoebiasis form?
Cysts
What are the symptoms of Amoebiasis?
Bloody diarrhoea
Bacteraemia
Liver abscess
What are the buzzwords for Amoebiasis?
Salad
Abroad
Bloody diarrhoea
Is the incubation period for norovirus short of long?
Short
How contagious is norovirus?
Very
How does norovirus spread?
Faecal to oral
Waterborn
What are the symptoms of norovirus?
Nausea
Vomiting
Diarrhoea
Cramps
How do you manage norovirus?
Self-limiting
Hydration
What most commonly causes gastroenteritis in children under 3?
Rotavirus
How does rotavirus spread?
Faecal oral
What is the seasonality of rota and norovirus?
Winter
What are the symptoms of rotavirus?
Mild watery to profuse diarrhoea
Shock
May have moderate fever first, then diarrhoea
Not bloody
How do you manage rotavirus?
Self-limiting
Lasts a week
What is the incubation period of Staph aureus and Bacillus cereus?
1-6 hours
What is incubation period of Salmonella and E. coli?
12-48 hours
Wha tis the incubation period of Shigella and Campylobacter?
48-72 hrs
What is incubation period of Giardiasis and Amoebiasis?
> 7 days
What is the incubation period of Cholera?
1-9 days
How do you treat Campylobacter if systemic features`
Erythromycin or ciprofloxacin
How do you treat salmonella if systemic features?
Ciprofloxacin
How do you treat Giardiasis?
PO metronidazole
How do you treat enterobius vermicularis?
PO mebendazole
How do you treat Slamonella typhi, paratyphoid?
Ceftriaxone OR Azithromycin OR Ciprofloxacin