Gastritis

Question 1

What is gastritis?

Answer 1

When the stomach mucosal lining becomes inflamed and injured

Question 2

What can cause gastritis?

Answer 2

H pylori
Autoimmune disease (related to pernicious anaemia and anti-IF antibodies)
Mucosal ischaemia
Campylobacter
Guillain Barre syndrome
Alcohol
CMV

Question 3

NSAIDs can cause g______ with is injury without inflammation

Answer 3

gastropathy

Question 4

What are gastritis symptoms?

Answer 4

Epigastric pain with diarrhoea
N+V
Indigestion

Question 5

How is gastritis diagnosed?

Answer 5

If H pylori detected: stool antigen test, urea breath test

Gold standard = endoscopy and biopsy

Question 6

What is treatment for H. pylori?

Answer 6

Triple therapy, CAP:
Clarithromycin
Amoxicillin
PPI

Question 7

What is a complication of gastritis?

Answer 7

Peptic Ulcer Disease

Question 8

H. pylori is a c_____ in the stomach which doesn’t normally cause diarrhoea, has low virulence but is typically o_____

Answer 8

commensal
opportunistic

Question 9

H. pylori causes _____ somatostatin (regulates endocrine system)

Answer 9

decreases

Question 10

True or false: H pylori decreases luminal bicarbonate

Answer 10

True

Question 11

H pylori secretes ____ which turns urea to carbon dioxide and ammonia

Answer 11

urease

Question 12

The ammonia produced due to urease action (from H pylori) is converted to toxic _____

Answer 12

ammonium

Question 13

H pylori causes ______ gastrin release

Answer 13

Increased

Question 14

Autoimmune gastritis affects stomach f____ and particularly causes ______ of ______ cells

Answer 14

fundus
atrophy
parietal