Gas Transport & Erythrocyte Physiology

Question 1

What is the normal blood hemoglobin levels in an adult male and adult female?

Answer 1

Male: 15.5 g/dL

Female: 14 g/dL

Question 2

Which of the following represents decreased affinity for O2?

A. Left shift in oxygen dissociation curve

B. Polycythmia and Methemoglobinemia

C. Right shift in oxygen dissociation curve

D. A and B

Answer 2

Right shift in oxygen dissociation curve

Question 3

List causes of a Right Shift in the oxygen dissociation curve

Answer 3

Exercise

Anemia

Increased H+

Increased CO2

Increased temperature

Increased 2/3-BPG

Question 4

Eryhtropoiesis requires what 2 vitamins?

Answer 4

Vitamin B12 (cobalamin,cynocobalamin)

Folate (B9)

Question 5

Which of the following would you expect to see with Primary Polycythemia?

A. Hypoxia and high EPO, extra RBCs, and potentially an abnormal CO

B. Genetic low EPO, extra RBCs, incerase in total blood volume, increased viscosity, and normal CO

Answer 5

Genetic low EPO, extra RBCs, incerase in total blood volume, increased viscosity, and normal CO

Question 6

Which of the following would you expect to see with Secondary Polycythemia?

A. Hypoxia and high EPO, extra RBCs, and potentially an abnormal CO

B. Genetic low EPO, extra RBCs, incerase in total blood volume, increased viscosity, and normal CO

Answer 6

Hypoxia and high EPO, extra RBCs, and potentially an abnormal CO