Gamma-Glutamyl transferase (GGT) Flashcards

1
Q

Gamma-Glutamyl transferase (GGT) Is located in?
A. Pancreas
B. Canaliculi of pancreatic cells
C.liver cells
D. Canaliculi of hepatic cells

A

D. Canaliculi of hepatic cells

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2
Q

Catalyze the transfer of the y-glutamyl residue from y-glutamyl peptides to amino acids, H2O etc

A. Ast
B. Ck
C. Alanine transferase
D.ggt

A

D. GGT

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3
Q

The most donor of y-glutamyl in biological physiology is?

A. Glutathione
B. Collagen
C. Vitamin b6

A

A. Glutathione

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4
Q

Diagnosis of hepatobiliary disorders

A. Ast
B. Ggpt
C. Ggt
D. ALT

A

(GGT)

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5
Q

chronic alcoholism

A. Ast
B. Ggpt
C. Ggt
D. ALT

A

C. Ggt

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6
Q

Sensitive indicator/marker for ethanol intoxication.

A. Ast
B. Ggpt
C. Ggt
D. ALT

A

GGT

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7
Q

Marker for . Occult alcoholism, acute alcoholic hepatitis

A

GGT

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8
Q

Enzyme marker for abstention from alcohol consumption

A

Ggt

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9
Q

TRUE OR FALSE, ggt

Can also be used in assessing biliary duct abnormalities

A

True

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10
Q

TRUE OR FALSE IN GGPT

It does not affect cell membrane and microsomal fractions.

A

False it affects!!!

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11
Q

Level of GGT is ↑ in individuals undergoing ——

A. Warfarin therapy
B.alcohol therapy
C. Drug therapy
D. Dialysis

A

A. Warfarin therapy

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12
Q

Reaction product of Gamma-Glutamyl transferase (GGT)

A.glutamyl- peptide + L+ cysteinyglycine NADH
B. glutamyl- peptide + L+ cysteinyglycine NAD
C. glutamyl- peptide + L+ cysteinyglycine
D. glutamyl- pepsine+ L+ cysteinyglycine NADH

A

C. glutamyl- peptide + L+ cysteinyglycine

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13
Q

Assay for GGT

A. Adenylate Kinase (AK)
B. Szaz Assay
C. Karmen
D. Thymolphthalein monophosphate assay

A

B. Szaz Assay

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14
Q

The absorbance of GGT is _______

a. p-Nitroaniline
b. p-nitrophenol

A

a. p-Nitroaniline

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15
Q

absorbance measured in GGT

A. 405-420NM
B. 409-420NM

A

A. 405-420NM

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16
Q

400-700nm WAVELENGTH
WILL PRODUCE?
A. COLORED
B.COLORLESS

A

A. COLORED

17
Q

<400/ >700 NM WAVELEGTH WILL PRODUCE

A. COLORED/ VISIBLE
B.COLORLESS/ NON VISIBLE

A

B.COLORLESS/ NON VISIBLE

18
Q

<400 NM

A. UV
B. INFRARED REGION

A

A. UV

19
Q

> 700 nm

A. UV
B. INFRARED REGION

A

B. INFRARED REGION