Alp Isoenzymes

Question 1

Two fractions of LIVER ALP

Answer 1

MAJOR LIVER. And .FAST LIVER

Question 2

predominant in serum; responsible for
liver ALP abundance; healthy individuals

A.fast liver
B. Major liver

Answer 2

Major liver

Question 3

(α1) band – closest to the anode; responsible for fast migration of the liver ALP

A.major
B. Fast liver

Answer 3

B. Fast liver

Question 4

Second fastest to migrate

A.liver alp
B. Bone alp
C. Placenta alp
D.intestinal alp

Answer 4

B. Bone alp

Question 5

Bone disorder: Osteitis deformans also known as ——disease

A.panget disease
B.pagets disease
C. Osteoblast disorder

Answer 5

pagets disease

Question 6

Most heat stable fraction
A.liver alp
B. Bone alp
C. Placenta alp
D.intestinal alp

Answer 6

C. Placenta alp

Question 7

3rd fastest to migrate

A.bone alp
B. Placental alp

Answer 7

Placental alp

Question 8

Placental alp will ↑ in pregnancy on how many weeks?

A.2-6 weeks of gastation
B. 16th to 20th weeks of gastation

Answer 8

B. 16th to 20th weeks

Question 9

Pathologic condition of placental alp is called

A. Carninoplacental alkaphose
B. Carcinoplacental acidosis

Answer 9

Carcinoplacental alkaphose

Question 10

Slowest moving fraction in Alp

Answer 10

Intestinal alp

Question 11

blood groups B or O secretors

A. Bone alp
B.placental alp
C. Intestinal alp

Answer 11

Intestinal alp

Question 12

when they consume fatty meals, ——- ALP are elevated

A. Bone
B.placental
C. Liver alp
D. Intestinal

Answer 12

Intestinal

Question 13

↑ in fatty meal consumption and GIT disorders

Answer 13

Intestinal alp

Question 14

In chemical inhbitors

A.bone
B.liver
C.intestinal

Answer 14

Intestinal

Question 15

Placental and Intestinal ALP are inhibited

A. Levamisole reagent
B. 3M urea
C. Phenylalanine

Answer 15

C. Phenylalanine

Question 16

used to inhibit Bone and Liver ALP

A. Levamisole reagent
B. 3M urea
C. Phenylalanine

Answer 16

Levamisole reagent

Question 17

inhibit the Bone ALP

A. Levamisole reagent
B. 3M urea
C. Phenylalanine

Answer 17

3M UREA

Question 18

Total ALP elevation by Liver or Bone ALP is differentiated by heating of serum at ——

A.8c for 10mins
B.50c for 10 mins
C.56c for 10mins

Answer 18

C.56c for 10mins

Question 19

When heated at 56c for 10 mins
Liver ALP residual activity is

A. ↓ to >20% (greater than)
B. ↓ to <20% (less than)

Answer 19

A. ↓ to >20% (greater than)

Question 20

When heated at 56c for 10 mins
BONE alp residual activity is

A. ↓ to >20% (greater than)
B. ↓ to <20% (less than)

Answer 20

B. ↓ to <20% (less than)

Question 21

most stable to labile Arrangement

A. Placenta>Intestine>Liver>Bone
B. Placenta>Liver>Bone>Intestinal

Answer 21

A. Placenta>Intestine>Liver>Bone

Question 22

the focus because is the major isoenzyme in the serum

A. Bone alp
B. Liver alp
C. Intestinal alp

Answer 22

A and B

Question 23

used in diagnosing cancer; could also be used as tumor marker

A. Nagao ALP
B. Regan ALP
C. Carcinoplacental ALP

Answer 23

C. Carcinoplacental ALP

Question 24

Breast, Lung, and Gynecological cancers

A. Nagao ALP
B. Regan ALP
C. Carcinoplacental ALP

Answer 24

B. Regan ALP

Question 25

Bone ALP co-migrator

A. Nagao ALP
B. Regan ALP
C. Carcinoplacental ALP

Answer 25

B. Regan ALP

Question 26

Adenocarcinoma of the pancreas and Bile duct, Pleural Cancer

A. Nagao ALP
B. Regan ALP
C. Carcinoplacental ALP

Answer 26

A. Nagao ALP

Question 27

used to inhibit Regan and Nagao

A. L-leucine
B. Phenylalanine

Answer 27

B. Pheny

Question 28

used to inhibit Nagao only

Answer 28

L- leucine