Alp Isoenzymes Flashcards

1
Q

Two fractions of LIVER ALP

A

MAJOR LIVER. And .FAST LIVER

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2
Q

predominant in serum; responsible for
liver ALP abundance; healthy individuals

A.fast liver
B. Major liver

A

Major liver

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3
Q

(α1) band – closest to the anode; responsible for fast migration of the liver ALP

A.major
B. Fast liver

A

B. Fast liver

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4
Q

Second fastest to migrate

A.liver alp
B. Bone alp
C. Placenta alp
D.intestinal alp

A

B. Bone alp

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5
Q

Bone disorder: Osteitis deformans also known as ——disease

A.panget disease
B.pagets disease
C. Osteoblast disorder

A

pagets disease

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6
Q

Most heat stable fraction
A.liver alp
B. Bone alp
C. Placenta alp
D.intestinal alp

A

C. Placenta alp

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7
Q

3rd fastest to migrate

A.bone alp
B. Placental alp

A

Placental alp

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8
Q

Placental alp will ↑ in pregnancy on how many weeks?

A.2-6 weeks of gastation
B. 16th to 20th weeks of gastation

A

B. 16th to 20th weeks

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9
Q

Pathologic condition of placental alp is called

A. Carninoplacental alkaphose
B. Carcinoplacental acidosis

A

Carcinoplacental alkaphose

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10
Q

Slowest moving fraction in Alp

A

Intestinal alp

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11
Q

blood groups B or O secretors

A. Bone alp
B.placental alp
C. Intestinal alp

A

Intestinal alp

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12
Q

when they consume fatty meals, ——- ALP are elevated

A. Bone
B.placental
C. Liver alp
D. Intestinal

A

Intestinal

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13
Q

↑ in fatty meal consumption and GIT disorders

A

Intestinal alp

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14
Q

In chemical inhbitors

A.bone
B.liver
C.intestinal

A

Intestinal

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15
Q

Placental and Intestinal ALP are inhibited

A. Levamisole reagent
B. 3M urea
C. Phenylalanine

A

C. Phenylalanine

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16
Q

used to inhibit Bone and Liver ALP

A. Levamisole reagent
B. 3M urea
C. Phenylalanine

A

Levamisole reagent

17
Q

inhibit the Bone ALP

A. Levamisole reagent
B. 3M urea
C. Phenylalanine

18
Q

Total ALP elevation by Liver or Bone ALP is differentiated by heating of serum at ——

A.8c for 10mins
B.50c for 10 mins
C.56c for 10mins

A

C.56c for 10mins

19
Q

When heated at 56c for 10 mins
Liver ALP residual activity is

A. ↓ to >20% (greater than)
B. ↓ to <20% (less than)

A

A. ↓ to >20% (greater than)

20
Q

When heated at 56c for 10 mins
BONE alp residual activity is

A. ↓ to >20% (greater than)
B. ↓ to <20% (less than)

A

B. ↓ to <20% (less than)

21
Q

most stable to labile Arrangement

A. Placenta>Intestine>Liver>Bone
B. Placenta>Liver>Bone>Intestinal

A

A. Placenta>Intestine>Liver>Bone

22
Q

the focus because is the major isoenzyme in the serum

A. Bone alp
B. Liver alp
C. Intestinal alp

23
Q

used in diagnosing cancer; could also be used as tumor marker

A. Nagao ALP
B. Regan ALP
C. Carcinoplacental ALP

A

C. Carcinoplacental ALP

24
Q

Breast, Lung, and Gynecological cancers

A. Nagao ALP
B. Regan ALP
C. Carcinoplacental ALP

A

B. Regan ALP

25
Bone ALP co-migrator A. Nagao ALP B. Regan ALP C. Carcinoplacental ALP
B. Regan ALP
26
Adenocarcinoma of the pancreas and Bile duct, Pleural Cancer A. Nagao ALP B. Regan ALP C. Carcinoplacental ALP
A. Nagao ALP
27
used to inhibit Regan and Nagao A. L-leucine B. Phenylalanine
B. Pheny
28
used to inhibit Nagao only
L- leucine