Gametogenesis Part 1 Flashcards
what is gametogenesis
production of sex cells
haploid (n) - diploid (2n) through meiosis
these are the progenitor cells of gametes
primordial germ cells or primary undifferentiated stem cells
the primordial germ cell appears at _______ and migrates to ______
wall of yolk sac at 3rd wk of development
migrates to gonads at 4th-5th wk
discuss the concept of mitosis
cell duplication for SOMATIC CELLS - replaces worn out cells
= 2 identical daughter cells
interphase - prophase - metaphase - anaphase - telophase
INTERPHASE of mitosis
chromosomes become double stranded
PROPHASE of mitosis
chromatid + chromatid = chromosome joined by centromere - begins to condense and thicken
starts to move towards opposite poles
microtubules produce mitotic spindles that attach to centrosomes
PROMETAPHASE of mitosis
mitotic spindle attaches to kinetochores
nuclear membrane breaks down allows fibers to attach to side of chromosomes at kinetochore
METAPHASE of mitosis
chromosomes are line up at equatorial plane at METAPHASE PLATE
centrioles have finished moving to opposite sides of cell
ANAPHASE of mitosis
centromeres split in 2 - spindle fibers contract and moves toward opposite poles
sister chromatids become chromosomes
TELOPHASE of mitosis
chromosomes arrive at opposite poles - decondenses, uncoils and lengthens
nuclear envelope material surrounds each set
CYTOKINESIS of mitosis
division of cytoplasm
begins at anaphase but ends after telophase
what is meiosis
division in germ cells to produce gametes
2 cell divisions - meiosis 1 and 2 para haploid
46 - 23
PROPHASE 1 of meiosis 1
- leptotene: chromosomes condense = 2 sister chromatids and centromere
- zygotene: 2 chromosome in each pair associate via synapsis
- pachytene - the pair trades DNA via crossing over
- diplotene: synapsis ends c disappearance of synaptonemal complex but homologous pairs still attached via chiasmata
- diakinesis: chromosomes are full condensed and nuclear membrane disintegrates
METAPHASE 1 of meiosis 1
microtubules emerge from spindle and attach to kinetochore and aligns at equator
attaches to maternal and paternal of homologous chromosome
METAPHASE 1 of meiosis 1
each homologous chromosome is pulled towards opposite poles - equal division of DNA
each daughter cells has half of chromosome from patent