Cerebral Palsy Flashcards

1
Q

what is cerebral palsy

A

nonprogressive but changing motor impairment syndromes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

when does CP develop

A

in utero until 6 yo

basta developing brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

discuss little’s disease

A

spastic diplegia type

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

most common antenatal cause

A

prematurity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

most common perinatal cause

A

asphyxia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

most common cause overall

A

prematurity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

low levels of iodine

A

diplegia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

exposure to organic mercury

A

quadriplegia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

intrauterine subdural hemorrhage

A

hemiplegia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

discuss how infection causes CP

A

fetoplacental or uterine infection causes preterm labor and inc cytokines = PVL

chorioamniotis - most common assoc c CP

TORCHS - 5%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

discuss how multiple gestation causes CP

A

at risk for preterm, growth restriction and low birth weight

twinning is the strongest risk factor bcs death = CP on surviving

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

discuss how pregnancy complications causes CP

A

thrombophilias - injury to placenta and clotting of fetal vessels

hemorrhage and preeclampsia - premature delivery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

discuss how birth asphyxia causes CP

A

cord coiling. pelvic disproportion and poor contraction of uterus

meconium aspiration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

discuss how prematurity causes CP

A

under 800g

APGAR of less than 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

discuss how Hyperbiliribinemia causes CP

A

G6PD can lead to CP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

postnatal causes of CP

A

stroke, clotting prob, AVM

drowning

head trauma

meningitis/encephalitis

cardiopulmo arrest

17
Q

how does magnesium sulfate treat CP

A

for preterm labor - inc seizure threshold in mothers c preeclampsia

can reduce risk of CP and protections

18
Q

how does antibiotics treat CP

A

reduces infections = dec chorioamniotis

19
Q

how does corticosteroids treat CP

A

inhibits cytokines = dec PVL

20
Q

which pathologies is the premature brain susceptible to

A

IVH

PVL - related to CP

both affect corticospinal = CP

21
Q

what is PVL

A

WM in the perieventricular region is underdeveloped or damaged

from ischemia or infection

22
Q

what is IVH

A

bleeding into the ventricles of brain = prob in development

23
Q

discuss BG lesions

A

high correlation c early jaundice

kernicterus - bilirubin encephalopathy
- dyskinetic CP

24
Q
A