G543 - Turning To Crime: Biology - Raine Et Al Flashcards
What type of scanning method was used?
PET scanning (positron emission tomography)
What was the aim?
To determine whether there is a biological basis for criminality
How many criminals were studied?
39 males 2 females
What were the criminals charged with?
Murder or manslaughter in california
What did they all plead?
Not guilty by reason of insanity (NGRI)
What were the 7 reasons for referral?
>Schizophrenia >head injury or organic damage >psychoactive drug abuse >affective disorder >epilepsy >hyperactivity or learning disorder >personality disorder
How many participants were in the control group?
41
What were the control group matched on?
Sex and age. 6 schizophrenics were also matched with the schizophrenics in the experimental group
What do you need to inject into the participant for PET scanning?
A tracer - flurodeoxyglucose or FDG.
What is the tracer taken up by?
The active areas of the brain. The more glucose taken up the more active the brain area is
What were participants given while having a PET scan?
A continuous performance task (CPT)
What lobes does the CPT specifically aim to activate?
The frontal lobes and the right temporal and parietal lobes.
Where did murderers have significantly reduced activity?
Both sides of the prefrontal cortex, the posterior parietal cortex and the corpus callosum
Where were there abnormal asymmetries?
Amygdala, thalamus and hippocampus
Which hemisphere had lower activity compared to the control group
The left hemisphere had lower activity than the right hemisphere in contrast with the control group