G543 - Turning To Crime: Biology - Brunner Flashcards
What experiment was used?
Quasi
What was the aim?
To explain the behaviour of a large family in the Netherlands where the males are affected by borderline mental retardation and abnormal violent behaviour
How many of the males from the family did the study closely examine?
5 affected males
What was the data collected from?
Urine samples
How long was data collected for?
24-hours
What did the urine tests show a deficit of?
Monoamine oxidase A (MAOA)
Where was a mutation identified?
On the X chromosome of the gene responsible for the production of MAOA
What is MAOA involved in?
Serotonin metabolism
What is a defect in the gene responsible for the production of MAOA likely to be responsible for?
Mental retardation in the family and this May account for their violent behaviour
What did Brunner fundamentally conclude about the MAOA deficiency?
It accounted for their inability to control aggression