G Reactive Proteins Flashcards
These endocrine molecules bind cell surface receptors and work thru G reactive proteins
Proteins + Polypeptides
75% of _____ are transduced w/ G-protein coupled receptors
SMAs (Styrene Maleic Acid)
Name the 4 functions/actions of G Reactive Protein
- Open specific membrane channel
- Activate cAMP or cGMP
- Activate enzymes
- Activate gene transcription
G Reactive Proteins open a membrane channel specific for _____, such as:
Ion species
Na+ or K+
What is different btwn G reactive protein membrane channels and typical ligand-gated channels?
G Reactive Proteins keep membrane channels open for a longer period of time
Define cAMP
Cyclic Adenosine MonoPhosphate
Define cGMP
Cyclic Guanosine MonoPhosphate
G reactive proteins activate ___ or ___
cAMP or cGMP
What do cAMP/cGMP stimulate?
Specific metabolic machinery in the neuron
G reactive proteins activate enzymes. What do enzymes initiate and where?
Biochemical rxns in target cell
G reactive proteins activate gene _____ and _____.
Transcription + protein synthesis
G reactive proteins activate gene transcription + protein synthesis. Gene transcription + protein synthesis may alter __________.
Metabolism or Morphology of the cell