Endocrine Molecules Flashcards
Name the 3 classes of endocrine molecules
Proteins + Polypeptides
Steroids
Derivatives of AA Tyrosine
What is the structure (+location) of Proteins + Polypeptide endocrine molecules?
Contain AAa
Stored in secretory vesicles (until needed)
How do Protein + Polypeptide endocrine molecules function?
Bind cell surface receptors
Work thru G-reactive proteins
~__% of SMAs are transduced w/ G-protein coupled receptors
(Styrene maleic acid)
75%
75% of SMAs are transduced w/ ___________.
G-protein coupled receptors
What is the structure of Steroid endocrine molecules?
Cholesterol derivative; lipid soluble
What is the location + transport of Steroid endocrine molecules?
NOT stored in cell
Needs transport plasma protein to travel thru blood
What produces + secretes Steroids?
Adrenal cortex, ovaries, testes, placenta
Where are Derivatives of Tyrosine endocrine molecules produced?
Thyroid, Adrenal medulla
Which Tyrosine derivatives are secreted by the thyroid?
Thyroid Hormones
Name the 2 Thyroid hormones
T4 - Thyroxine
T3 - Triiodothyronine
T4 comprises __% of thyroid hormones
Thyroxine, 97%
T3 comprises __% of thyroid hormones
Triiodothyronine, 3%
Which thyroid hormone is Inactive?
T4 - Thyroxine
Which thyroid hormone is Active?
T3 - triiodothyronine