Endocrine Molecules Flashcards

1
Q

Name the 3 classes of endocrine molecules

A

Proteins + Polypeptides
Steroids
Derivatives of AA Tyrosine

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2
Q

What is the structure (+location) of Proteins + Polypeptide endocrine molecules?

A

Contain AAa
Stored in secretory vesicles (until needed)

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3
Q

How do Protein + Polypeptide endocrine molecules function?

A

Bind cell surface receptors
Work thru G-reactive proteins

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4
Q

~__% of SMAs are transduced w/ G-protein coupled receptors

A

(Styrene maleic acid)
75%

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5
Q

75% of SMAs are transduced w/ ___________.

A

G-protein coupled receptors

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6
Q

What is the structure of Steroid endocrine molecules?

A

Cholesterol derivative; lipid soluble

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7
Q

What is the location + transport of Steroid endocrine molecules?

A

NOT stored in cell
Needs transport plasma protein to travel thru blood

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8
Q

What produces + secretes Steroids?

A

Adrenal cortex, ovaries, testes, placenta

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9
Q

Where are Derivatives of Tyrosine endocrine molecules produced?

A

Thyroid, Adrenal medulla

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10
Q

Which Tyrosine derivatives are secreted by the thyroid?

A

Thyroid Hormones

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11
Q

Name the 2 Thyroid hormones

A

T4 - Thyroxine
T3 - Triiodothyronine

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12
Q

T4 comprises __% of thyroid hormones

A

Thyroxine, 97%

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13
Q

T3 comprises __% of thyroid hormones

A

Triiodothyronine, 3%

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14
Q

Which thyroid hormone is Inactive?

A

T4 - Thyroxine

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15
Q

Which thyroid hormone is Active?

A

T3 - triiodothyronine

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16
Q

Which Tyrosine derivatives are produced in the Adrenal Medulla?

A

Catecholamines

17
Q

Name the 3 Catecholamines

A

Dopamine, Norepinephrine, Epinephrine

18
Q

Tyrosine-derived Thyroid hormones biochemically function like _____.

A

Steroids

19
Q

What Tyrosine derivative functions like steroids?

A

Thyroid hormones

20
Q

Tyrosine-derived Catecholamines function like _______.

A

Polypeptide hormones

21
Q

What Tyrosine derivative functions like polypeptide hormones?

A

Catecholamines