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Toxicology > Fungicide > Flashcards

Fungicide Flashcards

1
Q

What is the main hazard of fungicide?

A

see dressing

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2
Q

What are the clinical organo-mercury compounds?

A

CNS action

no longer used

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3
Q

What are the clinical sign of thiram? where are they found

A

canola seed dressing
hepatotoxic, skin irritant
- relatively low toxic

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4
Q

Where are chlorophenols used?

A

wood preservatives, molluscacide, rug shampoo, herbicide

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5
Q

What are pentachlorophenols? MOA?

A

powerful uncoupler of oxidative phosphorylation

inactivates resp enzymes direct irritant

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6
Q

What are the clinical signs of pentachlorophenols?

A

muscle weakness, incoordination, anorexiam BT1, dyspnea, sweating, dehydration, irritation (skin, resp tract, cardiac malfunction, terminal convulsions)

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7
Q

What is the excretion and absorption of pentachlorophenols?

A

rapid absorption and excretion (glucuronide formation)

- half life in cattle = 2d

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8
Q

What is the treatment for pentachlorophenols?

A

cold water bath, wash or purgative oxygen, lavage

emesis

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9
Q

what is the PM findings with pentachlorophenols?

A

congestion

some hemorrhage

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10
Q

What are the DDx with pentachlorophenols?

A

heat stroke, resp distress syndromes

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11
Q

What is seen with carbamate fungicides?

A

depression anorexia, diarrhea

no inhibition of cholinesterase enzymes

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12
Q

What is found on PM with carbamate fungicides?

A

liver + kidney degen
lungs - congestion
thyroid hyperplasia (chronic)

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13
Q

What carbamate fungicide are sheep susceptible to?

A

Zineb

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14
Q

What are the symptoms of Captan?

PM?

A

dyspnea, anorexia, depression

PM
- hydrothorax, ascites, gatroenteritis

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15
Q

What is the MOA of dinitrooorthocresol?

A

uncouples oxidative phosphorylation

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16
Q

What are the symptoms of dinitrooorthocresol?

A 
fever, weakness, dyspnea, anorexia
acidosis
liver/kidney damage
\+/- abortion
stains organs yellow
17
Q

What is the Tx fordinitrooorthocresol?

A 
lavage
HCO3
AC
cathartic
ice packs
18
Q

What does sulfur cause?

A

irritation > superpurgation, diarrhea, colic, dullness, ataxia
erythema
gastroenteritis, uclers, erosions (abomasum)
liver + kidney congestion
no residue concerns

19
Q

What does thiabendazole cause?

A

also anthelminthic
depression, anorexia
GIT disturbances

Toxicology (27 decks)

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