Fungi: Yeasts Flashcards
(T/F) Cryptococcosis can be a local or disseminated disease.
True
Which animal is a common carrier for cryptococcosis?
birds
Which species is primarily affected by cryptococcosis?
cats
(T/F) Cryptococcosis is often subclinical.
True
Which species causes cryptococcosis?
cryptococcus neoformans
Cryptococcus neoformans is urease (positive/negative).
positive
The disseminated form of cryptococcosis causes what kind of infection?
CNS
What two virulence factors are primarily associated with cryptococcosis?
capsule
melanin
________ functions in downregulating antibody formation, ROS toxicity, lymphocytes, and cytokines in Cryptococcus.
melanin
What primary antimicrobial is used to treat Cryptococcosis?
fluconazole
What kind of stain can be used to visualize the capsule and ID cryptococcus?
india ink wet mount
Which genus of fungi are secondary opportunistic pathogens which infect severely immunocompromised hosts but are common inhabitants of the GI tract?
candida
Which species of fungi causes Candidiasis?
candida albicans
________ has an issue with drug resistance.
candidiasis
What do you need to see histologically to identify candida albicans?
tissue invasion
What species of fungi is commensal in skin and an opportunistic pathogen?
malassezia
Which species of Malassezia affects dogs?
M. pachydermatis
What disease does Malassezia pachydermatis cause pruritis and waxy discharge of ears in dogs?
otitis externa
What species of Malassezia affects human skin is a cause of dandruff?
malassezia globosa
What species of fungi causes Sporotrichosis?
Sporothrix schenckii
(T/F) Sporothrix schenckii is nutritionally dimorphic.
False - thermally dimorphic
What unique shape does Sporothrix schenckii yeast appear as?
cigar shape
What species presents with ascending lymphocutaneous infection of the legs with Sporotrichosis?
horses
In (cats/dogs) the disseminated form of Sporotrichosis with necrotic lesions is more common.
cats
Two treatments for Sporotrichosis.
itraconazole
potassium iodide (feed)
