Fungi: Systemics

Question 1

Systemic fungal infection is a disease of (monomorphic/dimorphic) fungi.

Answer 1

dimorphic

Question 2

List the 3 main systemic fungal diseases.

Answer 2

1. histoplasmosis
2. blastomycosis
3. coccidioidomycosis

Question 3

Which fungal species causes histoplasmosis?

Answer 3

histoplasma capsulatum

Question 4

(T/F) Histoplasma capsulatum is a facultative intracellular fungi.

Answer 4

False - obligate intracellular

Question 5

Histoplasmosis causes granulomatous, primary _______ infection which can disseminate to other regions.

Answer 5

pulmonary

Question 6

_____ can be asymptomatic carriers of Histoplasma capsulatum.

Answer 6

bats

Question 7

(T/F) Cats with histoplasmosis are mostly affected by respiratory infection and the GI tract is not involved.

Answer 7

True

Question 8

What characteristic structure is seen when culturing histoplasma capsulatum?

Answer 8

tuberculated macroconidia

Question 9

(T/F) Histoplasmosis is zoonotic and therefore, can be a public health concern.

Answer 9

False

Question 10

Match the characteristics to their systemic fungal disease:

1. large, budding yeasts + microconidia
2. spores + spherules
3. small, single budding yeasts

Answer 10

1. blastomycosis
2. coccidioidomycosis
3. histoplasmosis

Question 11

Which fungi species causes blastomycosis?

Answer 11

blastomyces dermatitidis

Question 12

Blastomycosis causes granulomatous, suppurative, primarily pulmonary infection which can disseminate to eyes and ______.

Answer 12

bones

Question 13

(T/F) Blastomycosis is uncommon in cats but has a good prognosis.

Answer 13

False - uncommon but poor prognosis

Question 14

What species of fungi causes coccidioidomycosis?

Answer 14

coccidioides immitis

Question 15

Allyamines, azoles, echinocandin, polyenes, and pyrimidine inhibitors are all examples of ________.

Answer 15

anti-fungal treatments

Question 16

Coccidioides immitis produce “bags of spores” called:

Answer 16

spherules

Question 17

Coccidioidomycosis is associated with ______ disturbance.

Answer 17

soil

Question 18

_________ can be primarily pulmonary, acute progressive pulmonary, or chronic disseminated disease.

Answer 18

coccidioidomycosis

Question 19

_______ are resident carriers of Coccidioides immitis.

Answer 19

rodents

Question 20

Chronic Disseminated Coccidioidomycosis is defined as a progressive ______ infection/erosion.

Answer 20

bone