Functions of lymphoid organs Flashcards
What are B lymphocytes involved in?
Production of antibodies
What are T lymphocytes involved in?
Production of effector T cells
What does humoral immunity involve?
aka antibody-mediated immunity. Involves helper T cell and B cells
What does cellular immunity involve?
involves phagocytes, cytotoxic T cells, cytokines and chemokines
Where does the production of T/B lymphocytes take place?
The bone marrow
What happens during the maturation of T/B lymphocytes?
Acquirement of specific features or structures that enable them to recognise and interact with the pathogens.
Develop B and T cell receptors.
What happens in the activation of lymphocytes?
Reaction of lymphocytes with the pathogens to induce an immune response that is specific to that pathogen
What is the role of the lymphatic system?
transport of white blood cells
drainage of tissue
absorption and transport of fatty acids and fats
immunity
What are the different parts of lymphatic system?
-lymphatic vessels
-primary lymphatic organs (bone marrow and thymus)
-secondary lymphatic organs (lymph nodes,spleen,tonsil)
What happens in primary lymphoid organs?
Places where blood cells are produced and receive their ‘early training’
(acquire ability to interact with antigens)
Formation of blood cells in the bone marrow?
Hematopoiesis
Where is thymus located?
gland located below the larynx
what happens in thymus?
T cells are educated
what is cortex of thymus and what is in it?
outer region and has mature t lymphocytes
what is medulla of thymus and what is in it?
inner region and has immature T lymphocytes and macrophages
what happens in secondary lymphoid organs?
sites of lymphocyte activation by antigens
characteristics of lymph nodes?
Encapsulated, secondary lymphatic organs
500 lymph nodes
Situated throughout the body
Have access to antigens encountered in most tissues.
The main function is inducing adaptive immune responses to antigens carried from the tissues by lymph
Role of lymph nodes?
The main function of these nodes is to arrange a meeting and interaction between L and the different pathogens picked up from the tissue by the lymph with the aim of inducing adaptive immune responses against them.
how is adaptive immune response triggered?
-from antigen (carried from a specific tissue inside lymph nodes) through lymph
-macrophages (from circulation) carry antigen (antigen presenting cells)
-trigger adaptive immune response
Where is spleen located?
left upper quadrant of abdomen
What is contained in red pulp of spleen?
A blood filter: removing aging, damaged blood cells, particles: microorganism, opsonized microbes.
What is contained in white pulp of spleen?
mainly contains lymphocytes
Initiate immune responses to blood-borne antigens
What are the three phases of immune defense?
Recognition of danger
Production of specific weapons (Abs and Tc
Transport of weapons to site of attack
