Essential Pharmacology Part 3 - drugs and therapeutics

Question 1

How many receptor subtypes does one signalling mol act on?

Answer 1

several receptor subtypes

Question 2

What is a selective agonist?

Answer 2

drugs that activate only some of those receptors

Question 3

What is a selective antagonist?

Answer 3

are drugs that block only some of those receptors

Question 4

What is adrenaline?

Answer 4

neurotransmitter and hormone
released from adrenal medulla gland
binds to and activates all adrenoreceptors in the wide variety of tissues and organs

Question 5

What receptors can adrenaline bind to and what is its effects?

Answer 5

Alpha 1 receptors in the eye- dilates pupil
Alpha 2 receptors in the gut and inhibits gastric secretion
Beta 1 receptors in heart and increases heart rate
Beta 2 receptors on smooth muscle lining the airways and dilate airways

Question 6

What is salbutamol?

Answer 6

a selective beta2 agonist, used in treatment of asthma

Question 7

What is propranolol?

Answer 7

a selective beta1 and beta2 antagonist, used in treatment of arrhythmias