Frontiers 2021 Flashcards

1
Q

In Vladimír Jekl et al. Use of micro-CT imaging to assess ventral mandibular cortical thickness and volume in an experimental rodent model with chronic high phosphorus intake:

What location was chosen to measure the bone thickness in male degus?

note: full article not yet published. Abstract only as of 11-13-21

A

The micro-CT scanning, and wall thickness analysis was applied on region of the mandible exactly under the apices of the 4th premolar tooth, first and second molar tooth

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2
Q

In Vladimír Jekl et al. Use of micro-CT imaging to assess ventral mandibular cortical thickness and volume in an experimental rodent model with chronic high phosphorus intake:

Was mandibular bone thickness significantly thinner in the group fed a high phosphorus diet?

note: full article not yet published. Abstract only as of 11-13-21

A

Yes. Mandibular bone volume and thickness located apically to the premolar and molars were statistically significantly smaller/thinner in group fed by high phosphorus diet. The thinnest bone measured 0.004 mm, where the 4th premolar tooth almost perforated mandibular cortex.

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3
Q

Why are degus ideal for studies looking at the influence of different environmental, infectious, or metabolic factors on the growing tooth, alveolar bone formation, and bone pathologies?

A

Degus have continuously growing dentition, and the effect of any of the above listed factors can be studied in this animal model at any age and for longer time periods.

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4
Q

In Kendall Taney, Mark M. Smith, et. all. Risk Factors for Failure of Hard Palate Mucoperiosteal Flap Repair of Acquired Oronasal Communication in Dogs: A Pilot Study:

What percentage of cases resulted in failure (had a persistent oronasal fistula)?

A

25% (7/28 cases)

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5
Q

In Kendall Taney, Mark M. Smith, et. all. Risk Factors for Failure of Hard Palate Mucoperiosteal Flap Repair of Acquired Oronasal Communication in Dogs: A Pilot Study:

Which of the following risk factors were found to significantly increase risk of failure of flap repair?

  • increasing age,
  • sex,
  • increase in body weight,
  • presence of neoplasia at the time of surgery
  • presence of neoplasia after surgery (incomplete margins),
  • the use of CO2 laser
  • previous surgeries in the same location,
  • HPF blood supply
  • the size of the HPF (as a percentage of the total area of the hard palate mucoperiosteum)
  • distance traveled by the apex of the HPF
A

Within this sample, the presence of neoplasia at the time of initial surgery, increasing the area of the HPF, and distance traveled by the HPF apex were associated with a greater odds of HPF failure.

Patients with presence of neoplasia prior to surgery had a 4.5-fold odds of HPF failure compared to those without

BOTH Larger FLAP AREA and HIGHER APEX TRAVEL DISTANCE were SIGNIFICANTLY larger in cases of failure.

NO SIGNIFICANT DIFFERENCES:

  • in AGE or SEX
  • in MARGINS post op
  • to PREVIOUS PROCEDURES
  • BLOOD SUPPLY associated with failure.
  • the use of CO2 laser
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6
Q

In Kendall Taney, Mark M. Smith, et. all. Risk Factors for Failure of Hard Palate Mucoperiosteal Flap Repair of Acquired Oronasal Communication in Dogs: A Pilot Study:

Did bigger body weights increase or decrease the odds of failure?

A

Decreases (larger dogs have lower risk of failure):
For every kilogram increase in body weight, the odds of HPF failure decreased by 6%

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7
Q

In Kendall Taney, Mark M. Smith, et. all. Risk Factors for Failure of Hard Palate Mucoperiosteal Flap Repair of Acquired Oronasal Communication in Dogs: A Pilot Study:

Did neoplasia prior to ONF surgery increase or decrease the odds of failed surgery?

A

INCREASED

Patients with presence of neoplasia prior to surgery had a 4.5-fold odds of HPF failure compared to those without

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8
Q

In Frontiers The Frequency of Communication Between the Synovial Compartments of the Equine Temporomandibular Joint: A Contrast-Enhanced Computed Tomographic Assessment

Of the 20 horses, was communication found between the two synovial compartments of the equine TMJ?

A

No - there was no PHYSIOLOGICAL communciation between the DTJ and the DMJ in the horses studied. Two horses had PERFORATION of the intra-articular disc in the region of the caudomedial fibrous expansion

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9
Q

In Soukup et, al Incidence and Risk Factors for Surgical Site Infections Following Oromaxillofacial Oncologic Surgery in Dogs:

What percent of the 226 dogs included in this retrospective study developed surgical infection at the site of surgery?

A

7.5%

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10
Q

In Soukup et, al Incidence and Risk Factors for Surgical Site Infections Following Oromaxillofacial Oncologic Surgery in Dogs:

What was significantly assoociated with the development of infection?

A

Anesthetic events lasting more than 6 hours.

Signalment, comorbidities, administration of anti-inflammatory and immunosuppressive medications, tumor type, histological margin evaluation, surgical procedure location, and antibiotic protocols were not significant contributors to development of infection

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11
Q

In Soukup et, al Incidence and Risk Factors for Surgical Site Infections Following Oromaxillofacial Oncologic Surgery in Dogs:

Was the use of antibiotics in this cohert protective against the development of infection?

A

No

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12
Q

True or false:

A surgical site infection is defined by the Centers for Disease Control and Prevention (CDC) as a post-surgical infection that occurs _within 30 day_s of the surgical procedure (or within 1 year of an implant placement) and must include at least one of the following features: purulent debris; positive bacterial culture; or pain, swelling, heat, and redness at the surgical site

A

TRUE

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13
Q

The American Veterinary Dental College (AVDC) position statement recommends systemically administered antibiotics to reduce bacteremia in what subset of animals?

A

Animals with underlying systemic disease, such as sub-aortic stenosis or severe renal disease, and in the face of a severe oral infection.

The position statement addresses systemic antibiotic use but does not differentiate between prophylactic and therapeutic treatment.

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14
Q

In Soukup et, al Incidence and Risk Factors for Surgical Site Infections Following Oromaxillofacial Oncologic Surgery in Dogs:

The study found that 7.5% of the animals in this study developed infection. Specifically, what was the percentage of infection in animals who’s surgery was longer than 6 hour?

A

19.4%

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15
Q

Of the dogs in Soukup et, al Incidence and Risk Factors for Surgical Site Infections Following Oromaxillofacial Oncologic Surgery in Dogs

although not significantly significant (but close) – were dogs more or less likely to develop infection if their surgery was done in the dental suite and not the surgical suite.

A

Dogs were LESS likely to develop infection if the surgery was performed in the DENTAL suite and MORE likely to develop infection if the surgery was in the SURGICAL suite.

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16
Q

True or false:

In a retrospective cohort study including adults (human) who underwent a variety of elective surgical procedures, peri-operative prophylactic antibiotic therapy was not associated with risk for postoperative antibiotic-resistant infections

A

True

However, this does not address the significant risk of antibiotic resistance as it pertains to its effect on broader public health.

17
Q

There were a few variables that have previously been identified as potential risk factors for surgical site infection, including the ASA classification status, surgical time, and anesthetic complications (such as hypotension).

True or false:

These parameters were not considered in Soukup et, al Incidence and Risk Factors for Surgical Site Infections Following Oromaxillofacial Oncologic Surgery in Dogs – due to insufficient detail in the medical records.

A

True

18
Q

In : Fracture Resistance of Equine Cheek Teeth With and Without Occlusal Fissures: A Standardized ex vivo Model

In healthy teeth, what significantly influenced fracture resistance – state if there was a difference in the maxillary and mandibular teeth.

A

In healthy teeth

  • fracture resistance was significantly influenced by the location on the tooth where testing was performed in both maxillary (p < 0.001) and mandibular teeth (p < 0.001).
  • significantly associated factors were Triadan number in mandibular teeth (p = 0.009)
  • significantly associated with mesiodistal length of the occlusal surface of maxillary teeth (p = 0.01).
19
Q

In : Fracture Resistance of Equine Cheek Teeth With and Without Occlusal Fissures: A Standardized ex vivo Model

Did fissures significantly reduce fracturee loads compared to fissure free teeth?

A

Yes

20
Q

In : Fracture Resistance of Equine Cheek Teeth With and Without Occlusal Fissures: A Standardized ex vivo Model

What was the mean maximum force sustained by the tested HEALTHY teeth:

1373 N

2373 N

3373 N

4387 N

WAS THERE A SIGNIFICANT DIFFERENCE BETWEEN MAXILLARY AND MANDIBULAR TEETH?

A

The mean maximum force sustained by the tested teeth was 2,373.34 ± 583.94 N

NO

21
Q

In : Fracture Resistance of Equine Cheek Teeth With and Without Occlusal Fissures: A Standardized ex vivo Model

What location had the highest fracture resistance force in the mandible? In the maxilla?

A

In the mandible, the pulp horn 2 had the highest fracture resistance and pulp horn 5 had the lowest.

In the maxilla, pulp horn 4 had the highest fracture resistance and pulp horn 5 had the lowest.

22
Q

In : Fracture Resistance of Equine Cheek Teeth With and Without Occlusal Fissures: A Standardized ex vivo Model

What was the mean maximum force sustained by the teeth with fissures:

1373 N

1974 N

3373 N

4974 N

A

The mean maximum force sustained by teeth with fissures was 1,974.02 ± 402.09 N

23
Q

In : Fracture Resistance of Equine Cheek Teeth With and Without Occlusal Fissures: A Standardized ex vivo Model

Were teeth that fractured below the simulated bone margin more or less likely to have exposed pulp?

Was this significant.

A

MORE

Yes – found to be significant.

24
Q

In : Fracture Resistance of Equine Cheek Teeth With and Without Occlusal Fissures: A Standardized ex vivo Model

What factors were found to be significantly associated with fracture resistance in mandibular teeth?

A

location on the tooth (SD-PH 1-5) (p = 0.005), the age of the tooth (p = 0.006), the length of the tooth (p < 0.001) and the side of the jaw (left/ right) (p = 0.05) were significantly associated with a lower/higher fracture resistance

–> ALTHOUGH IN THE DISCUSSION SECTION IT STATES THAT THERE WAS NO SIGNIFICANCE BASED ON AGE OF TOOTH!!!

25
Q

In : Fracture Resistance of Equine Cheek Teeth With and Without Occlusal Fissures: A Standardized ex vivo Model

What factors were found to be significantly associated with fracture resistance in maxillary teeth?

A

In maxillary teeth, only the location on the tooth (SD-PH 1-5) (p < 0.001) demonstrated a significant association, and the fissure fracture type

26
Q

In Verstraete, Cissell, Arzi et al. The Diagnostic Yield of Cone-Beam Computed Tomography for Degenerative Changes of the Temporomandibular Joint in Dogs:

Based on the correlative results of statistical analysis, was CBCT found to be a suitable modality to evaluate DTMJ?

A

Yes

27
Q

In Verstraete, Cissell, Arzi et al. The Diagnostic Yield of Cone-Beam Computed Tomography for Degenerative Changes of the Temporomandibular Joint in Dogs:

What was the most prevalent finding radiologically and histologically with a fair to excellent agreement?

A

Subchondral sclerosis was the most prevalent finding radiologically and histologically with a fair to excellent agreement.

28
Q

In Verstraete, Cissell, Arzi et al. The Diagnostic Yield of Cone-Beam Computed Tomography for Degenerative Changes of the Temporomandibular Joint in Dogs:

What did they find with respect to the agreement between CBCT findings and histology when evaluating TMJ degenerative changes?

A

The more severe the TMJ degenerative changes, the higher the agreement between CBCT and histology

29
Q

What are two main differnces between apendicular joints and the TMJ?

A

The TMJ is a load bearing joint and the articulating surfaces is covered by fibrocartilage.

The appendicular synovial joints are weight bearing** and are coveered by **hyaline cartilage.

Note - the TMJ is also a synovial joint.

30
Q

What type of collagen makes up fibrocartilage (which lines the surfaces of the TMJ) vs the hyaline cartilage of appendicular joints?

Of the two types of cartilage, which withstands more shear and tension forces?

A

Fibrocartilage is unique as it contains both types I and II collagen , (whereas hyaline articular cartilage mainly contains type II collagen)

Fibrocartilage (TMJ) better suited to endure the gliding motion of the TMJ due to increased ability to withstand shear and tension forces.

31
Q

What was the most common finding on CBCT?

A

Bone sclerotic changes were the most common findings and noted in 33 out of the 38 mandibular heads (86.8%) and 36 out of the 38 (94.7%) of the mandibular fossae.

32
Q

On CBCT, was joint space narrowing a common finding?

A

Yes. 81% of TMJs evaluated had some degree of joint space narrowing. Most of the narrowing was on the LATERAL ASPECT of the joints.

33
Q

In Verstraete, Cissell, Arzi et al. The Diagnostic Yield of Cone-Beam Computed Tomography for Degenerative Changes of the Temporomandibular Joint in Dog

In the histological findings, was subchondrral sclerotic changes more common in the mandibular head or the mandublar fossas?

A

Subchondral sclerotic changes were more common in the mandibular fossa,

34
Q

In Verstraete, Cissell, Arzi et al. The Diagnostic Yield of Cone-Beam Computed Tomography for Degenerative Changes of the Temporomandibular Joint in Dog

What was the correlation between subchondral bone sclerosis and osteophytes found on CBCT and histological evaluation of the MANDIBULAR FOSSA?

A

Excellent – for sclerosis and osteophytes on the fossa; excellent for osteophytes on the head.

However just MODERATE agreement for sclerosis on the mandibular HEADS.

35
Q

In Verstraete, Cissell, Arzi et al. The Diagnostic Yield of Cone-Beam Computed Tomography for Degenerative Changes of the Temporomandibular Joint in Dog

In 2 dogs, they identified disc perforations. In these dogs, were there significant degenerative changes in the osseous components of the TMJ?

A

NO

36
Q

In Influence of Dietary Supplementation With a Powder Containing A.N. ProDen™ (Ascophyllum Nodosum) Algae on Dog Saliva Metabolome:

What is A. nodosum?

After 30 days of product administration, were there significant changes in dog saliva metabolomes?

True or false:

The exact mechanism of A. nodosum is still unclear and warrants further study. This study suggest that brown algae inhibit or turn off some pathways that could enhance plaque or calculus development.

A

A brown algae

Yes

True

37
Q
A
38
Q

True or false: The temporohyoid joint is a synchondrosis.

Fill in the blank: The epihyoid is an ossification center of the _______________and fuses with the _________ in two-thirds of horses_._

True or false: The lingual process has a separate ossification center.

A

True – The temporohyoid joint is a synchondrosis. T

he epihyoid is an ossification center of the stylohyoid and fuses with the stylohyoid in two-thirds of horses.

True – The lingual process has a separate ossification center.