Ax\ Flashcards

1
Q

Based on the american society of anesthesiologists physical status classification. Define:
P1 to P6

A

P1 A normal healthy patient

P2 A patient with mild systemic disease

P3 A patient with severe systemic disease

P4 A patient with severe systemic disease that is a constant threat to life

P5 A moribund patient who is not expected to survive without the operation

P6 A declared brain-dead patient whose organs are being removed for donor purposes

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2
Q

In The effectiveness of a long-acting transdermal fentanyl solution compared to buprenorphine for the control of postoperative pain in dogs in a randomized, multicentered clinical study

What pain scale was used?

With this scale what is the maximum score?

At what pain score were animals removed from this study.

A

modified Glasgow Composite Pain Scale with a dropout criteria of 8 and above; (20 maximum score)

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3
Q

True or false:

Spontaneous respirations are maintained independent of fentanyl concentration in dogs

A

True

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4
Q

Categorize the following patients for ASA status:

  1. controlled diabetes
  2. uncontrolled diabetes
  3. Extreme shock and dehydration
  4. GDV
  5. Emaciation
  6. skin tumour
  7. cryptorchidectomy
  8. moderate hypovolemia
  9. localized infection
  10. terminal malignancy
  11. Fever
  12. Anemia
  13. compensated cardiac disease
  14. Decompensated cardiac disease
  15. Severe fever
  16. Toxemia
  17. Uremia
A
  1. controlled diabetes – ASA 2
  2. uncontrolled diabetes – ASA 2
  3. Extreme shock and dehydration – ASA 5
  4. GDV – ASA 5 or E
  5. Emaciation – ASA 4
  6. skin tumour – ASA2
  7. cryptorchidectomy – ASA 2
  8. moderate hypovolemia – ASA 3
  9. localized infection – ASA 2
  10. terminal malignancy – ASA 5
  11. Fever – ASA 3
  12. Anemia – ASA 3
  13. compensated cardiac disease – ASA 2
  14. Decompensated cardiac disease – ASA 4
  15. Severe fever – ASA 4
  16. Toxemia – ASA 4
  17. Uremia – ASA 4 (any organ failre is 4)
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5
Q

True or false:

  • Studies demonstrate slightly longer recoveries following both propofol and alfaxalone in Greyhounds.
  • These results were initially ascribed to the large muscle mass and minimal adipose tissue found in Greyhounds and hence generalized to all sighthounds. However, more recent data have demonstrated that the Greyhound breed may have relative deficiencies in hepatic metabolism
A

Both TRUE

(Lumb and Jones)

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6
Q

True or False:

MAC of inhalent anesthetics seems to be lower in cats than dogs and horses.

Propofol clearance in cats is reported to be shorter than dogs.

A

TRUE - MAC is lower in cats

FALSE – propofol clearance in cats is slower –> reported to be at least twice as fast in DOGS as in CATS.

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7
Q

What effect causes higher doses of opioids to cause an increase HR, increased CO and increased BP in cats?

A

Increased catecholamine effect seemingly from increased doses of opioids in cats (biphasic effects)

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8
Q

In cats with tracheal rupture - what changes the prognosis whether treatment is likely successful (surgical and conservative)

A

Whether injury extends to carina. If does not extend into carina, then tx is usually successful.

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9
Q

What time period has the highest incidence of ax related deaths?

What percentage of cats, dogs and rabbits have reportedly died during this time period?

A

Within 3 hours of terminating a procedure

Cats - 60%

Dogs - 50%

Rabbits - 60%

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10
Q

In each of the following, state the approximate risk of Ax related death in percent:

Dog ASA 1-2 0.05%

Dog ASA 3-5 1.3%

Cat ASA 1-2 0.11%

Cat ASA 3-5 1.4%

Rabbit ASA 1-2 0.7%

Rabbit ASA 3-5 ~7%

A

Dog ASA 1-2

Dog ASA 3-5

Cat ASA 1-2

Cat ASA 3-5

Rabbit ASA 1-2

Rabbit ASA 3-5

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11
Q

What is the general risk of Ax death in small animals estimated to be?

In higher risk dogs and cats?

What is higher risk - dog or cat?

A

0.1-0.3%

1-4%

Cats appear at greater risk

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12
Q

True or false:

  • In cats, increasing ASA grade, procedural urgency, major versus minor procedures, increasing age, extremes of weight, endotracheal intubation, and the use of fluid therapy were associated with increased odds of anesthetic and sedation‐related death Pulse and pulse oximetry monitoring were associated with a reduction in odds.
  • In dogs, poorer health status (based on ASA grade), greater procedural urgency, major versus minor intended procedures, old age, and low weight were associated with anesthetic‐related death.
  • Increasing duration of the procedure and the anesthetic induction and maintenance combination used were not associated with increased odds of anesthetic‐related death
  • Halothane after IV induction had a 66 fold increase in odds of ax death than Isoflurane with IV induction.
A

TRUE

TRUE

FALSE (WERE associated)

TRUE

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13
Q

What factors make older patients more of a risk for ax?

A

More susceptible due to:

  • depressant effects of ax
  • impaired thermoregulatory mechanisms
  • reduced metabolism –> prolonged rovery
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14
Q

True or false:

IV fluids during ax is associated with increased risk odds of ax related death.

A

True

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15
Q

Does respiratory acidosis and metabolic acidosis contribute to hyperkalemia in greyhounds under GA?

A

Yes.

BES is better a better fluid choice than NaCl due to NaCl having acidifying effects.

ETCO2 important to maintain.

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16
Q

The Effect of Heart Disease on Anesthetic Complications During Routine Dental Procedures in Dogs Jennifer E. Carter, DVM 2017The Effect of Heart Disease on Anesthetic Complications During Routine Dental Procedures in Dogs Jennifer E. Carter, DVM 2017

How many dogs died that had heart disease?

In this study, what was the most common complication? Second most common?

A

No dongs died

Hypotension (49% of dogs in botoh groups)

and Bradycardia (35%)

17
Q

The Effect of Heart Disease on Anesthetic Complications During Routine Dental Procedures in Dogs Jennifer E. Carter, DVM 2017The Effect of Heart Disease on Anesthetic Complications During Routine Dental Procedures in Dogs Jennifer E. Carter, DVM 2017

What complication was significantly different between the two groups?

A

There were no significant differences between the two groups. The prevalence of complications between the two groups were the same.

18
Q

The Effect of Heart Disease on Anesthetic Complications During Routine Dental Procedures in Dogs Jennifer E. Carter, DVM 2017The Effect of Heart Disease on Anesthetic Complications During Routine Dental Procedures in Dogs Jennifer E. Carter, DVM 2017

What was the prevalence of complications?

A

The overall complication frequency was 82.5%

19
Q

Is etomidate (injectable anesthetic) suppressive to the cardiovascular system?

A

•etomidate is an injectable general anesthetic that produces minimal changes in myocardial function, HR, or blood pressure in dogs

20
Q

What is the maximum recommended dose for the following agents:

Lidocaine

Mepivacaine

Bupivacaine

Ropivacaine

A

Lidocaine - cat 6mg/kg; dog 10mg/kg

Mepivacaine - 10mg/kg

Bupivacaine - 2mg/kg

Ropivacaine - 3mg/kg

21
Q

IN Pharmacokinetics and pharmacodynamics of a constant rate infusion of fentanyl (5 μg/kg/h) in awake cats. Ambrose et al AJVR, Vol 75, No. 8, August 2014

Was a steady state of plasma fentanyl concentration achieved during the 2 hours of the CRI?

A

No - In the present study, plasma fentanyl concentration did not attain a constant level but gradually decreased from 4.41 to 2.99 ng/mL during the 2-hour CRI

22
Q

IN Pharmacokinetics and pharmacodynamics of a constant rate infusion of fentanyl (5 μg/kg/h) in awake cats. Ambrose et al AJVR, Vol 75, No. 8, August 2014

What plasma fentanyl concentration was necessary to have an antinociception effect?

A

plasma fentanyl concentrations ≥1.33 ng/mL were necessary to yield an antinociceptive effect.

23
Q

In Redondo J, Suesta P, Gil L, et al. Retrospective study of the prevalence of postanaesthetic hypothermia in cats. Vet Rec 2012; 170(8): 206.

What were the variables associated with a decrease in temperature recorded at the end of ax?

A
  • Duration of anaesthesia
  • Reason for anaesthesia (abdominal and orthopaedic surgeries significantly reduced the temperature when compared with minor procedures)
  • Anaesthetic risk (high-risk cats showed lower temperatures than low- risk cats).
  • The temperature before premedication was associated with an increase in the final temperature.
24
Q

In In Redondo J, Suesta P, Gil L, et al. Retrospective study of the prevalence of postanaesthetic hypothermia in cats. Vet Rec 2012; 170(8): 206.

What was the prevalence of slight hypothermia, moderate hypothermai and severe hypothermia?

A

•The prevalence of hypothermia was slight 26.5 %, moderate 60.4% and severe 10.5 %.

25
Q

In Redondo J, Suesta P, Serra I, et al. Retrospective study of the prevalence of postanaesthetic hypothermia in dogs. Vet Rec 2012; 171(15): 374.

What were the variables associated with a decrease in temperature recorded at the end of ax?

A
  • duration of the preanesthetic time
  • duration of the anaesthesia
  • physical condition (ASA III and ASA IV dogs showed lower temperatures than ASA I dogs)

• the reason for anaesthesia (anaesthesia for diagnostic procedures or thoracic surgery reduce the temperature when compared
with minor procedures)

  • recumbency during the procedure (sternal and dorsal recumbencies showed lower temperatures than lateral recumbency).
  • The temperature before premedication and the body surface (BS) were associated with a higher temperature at the end of the anaesthesia, and would be considered as protective factors.
26
Q

What is the main blood supply to the brain in a cat?

A

The maxillary artery which is a branch off of the external carotid artery.

27
Q

In cats, most of the brain’s blood supply is via the ______________, except the caudal part of the medulla oblongata, which is supplied by the _____________________-.

A

Maxillary arteries (branch of the external carotid)

the vertebral arteries.

The cat also receives a small contribution of arterial circle blood via the ascending pharyngeal artery, a branch off the common carotid artery

28
Q

Post-anesthetic cortical blindness in cats: Twenty cases J. Stiles a,⇑ , A.B. Weil a , R.A. Packer a,b , G.C. Lantz

How many of the 20 cats were anesthetized for dentistry?

A

13

29
Q

Post-anesthetic cortical blindness in cats: Twenty cases J. Stiles a,⇑ , A.B. Weil a , R.A. Packer a,b , G.C. Lantz

How many of the 20 cats with cortical blindness had a mouth gag inserted during the procedure?

A

16/20

30
Q

Post-anesthetic cortical blindness in cats: Twenty cases J. Stiles a,⇑ , A.B. Weil a , R.A. Packer a,b , G.C. Lantz

How many did vision recover?

What percentage had other neuro defecits in addition to blindness?

What percentage had full recovery from all neurologic disease?

A

70% (14/20)

85% had blindness with additional neuro deficits (circling, ataxia, head tilt, weakness, opisthotonus, decreased conscious proprioception, and abnormal mentation)

59%

31
Q

What artery enters into the foramen oval in a cat?

A

The middle meningeal artery (the mandibular branch of the trigeminal nerve also runs through the foramen oval)

32
Q

What arteries enter the orbital fissure?

A

Branches of the maxillary rete

33
Q

Between what muscles is the maxillary rete situated?

A

Between the medial and lateral pterygoid muscles and the temporal muscles.

34
Q
A