Fouty- V/Q Matching Flashcards
PiO2
150 mmHg
PH2O
47 mmHg
PAO2
100 mmHg
PACO2
40 mmHg
critical in determining O2 content and delivery
partial pressure of O2 in the alveolus
Alveolar gas equation: PAO2=
PAO2 = (Pb - PH2O) x FIO2 - PaCO2/R
LA PaO2
90 mmHg
normal A-a gradient
10-12mmHg
______ventilation is what is reacting with blood not minute ventilation
alveolar
normal V/Q ratio
1.0
goal: match ventilation w/
perfusion
hyperinflation
flat diaphragm
emphysema
emphysema
is ventilation normal or abnormal in emphysema
abnormal
ventilation normal or abnormal in asthma
abnormal
ventilation normal or abnormal in bronchiectasis
abnormal
ventilation normal or abnormal in bronchiolitis obliterans
abnormal
heart failure (pulmonary edema)
airspace disease is seen where and it impacts ventilation here
lingula (L heart border missing)
lobar pneumonia; impacts ventilation
pollution in the air can impair______ (causes bronchoconstriction)
ventilation
perfused but not ventilated
L and R
L: normal
R: severe asthma
what is affected by pulmonary embolism
perfusion
pulmonary embolism
shunt V/Q
0
shunting allows for what
V/Q matching elsewhere
low V/Q mismatch causes what
hypoxemia (perfused but not ventilated well)
high V/Q mismatch
ventilated but not perfused
___ and ____ contribute to arterial hypoxemia
shunt and low V/Q
_____ causes dead space and represent wasted ventilation
high V/Q
no air in alveolar space caused by what 2 main things
pneumonia and atelectasis
anatomic dead space
conduction zone
minute ventilation (VE)=
VA (alveolar ventilation) + VD (dead space)
____ controlled by CO2 production and alveolar ventilation
CO2
doesn’t cause hypoxemia, just increases work of breathing
dead space
VD (dead space)=
anatomic dead space + alveolar dead space
_____ of normal tidal volume at rest is dead space
1/3rd
rapid shallow breathing causes what
dead space
alveolar dead space due to pulmonary vascular disease, acute pulmonary embolus and decreased CO causes what
dead space
ventilation in excess of perfusion due to + pressure ventilation and emphysema causes what
dead space
causes what
dead space (due to pulm embolism)
_____ can lead to pulmonary artery and arteriole dropout (rarefication)—dead space
PAH
does NOT cause hypoxemia (due to no blood flow there)
high V/Q units
example of this is bronchial obstruction (mucous plug) causing atelectasis
shunt
best estimate of low V/Q mismatch
alveolar-arterial oxygen gradient (A-a)
how to get PaO2
ABG
how to get PAO2
alveolar gas equation
causes increased A-a gradient
low V/Q
shunt
(areas of perfused blood that is not getting oxygenated)
PaO2< 80mmHg
hypoxemia
5 main causes of hypoxemia
altitude
hypoventilation
diffusion
low V/Q mismatch
shunt
hypoxemia with normal A-a gradient due to
altitude
hypoventilation
hypoxemia with increased A-a gradient due to
diffusion
low V/Q mismatch
shunt
in this the capillary O2 is the same as venous O2
shunt
responds to low flow oxygen
low V/Q mismatch
anytime you have PAO2 > 120 mmHg, means what
Hb completely saturated (can’t take on anymore)
doesn’t respond to 100% oxygen
shunt
asthma
chronic bronchitis
emphysema
ILD
low V/Q
pneumonia
atelectasis
ARDS
CHD
anomalous venous return
shunt