Fouty- Pneumonia Flashcards
3 main bacteria that cause typical pneumonia
S. pneumoniae
H. influenzae
Moraxella catarrhalis
3 main things that cause atypical pneumonia
Chlamydia pneumoniae
Mycoplasma pneumoniae
viruses
3 main bugs that cause lobar pneumonia
S. pneumoniae
H. influenzae
Klebsiella
4 main bugs that cause bronchopneumonia
S. pneumoniae
H. influenzae
S. aureus
Moraxella
4 main things causing interstitial pneumonia
Chlamydia pneumoniae
Mycoplasma pneumoniae
Legionella
viruses
Coccidiomycosis spherule in lung
found in southwestern part of US and southern california
Coccidiomycosis
pulmonary ____
Coccidiomycosis
found in Ohio, Missouri, Illinois
Histoplasmosis and Blastomycosis
Histoplasmosis
pulmonary _____
Histoplasmosis
pulmonary ____
Histoplasmosis
“bowling pen”
Blastomycosis
route of entry for these
environmental inhalation
bronchopneumonia
gram - bacterium (intracellular)
Legionella pneumophila
exposure to water coolers, air conditioners, hotel where they may not clean air conditioners; lot of sputum production
Legionella pneumophila
route of entry for this is water sources (inhalation)
Legionella
route of entry through inhaling contaminated wool
Anthrax
_____ can cause interstitial lung disease and infectious disease
parrots and birds
pneumonia from birds
Chlamydia psittaci
pigeons can spread this
Histoplasma
cows can transmit this
group C strep
what bugs can cause group C strep from cows
B. anthracis
Coxiella burnetti
____can spread Q fever (Coxiella burnetti)
sheep
Birds, pigeons (mainly droppings) can spread what
Histoplasmosis
Anthrax (the sixth plague) spread from what animals
cow, sheep
parrots spread what
Chlamydia psittaci
Coxiella burnetti (Q fever) spread by what animals
cattle, sheep, goats
group C strep spread by what animal
cow
3 routes of entry for community acquired pneumonia:
aspiration
inhalation
hematogenous spread
due to fungus common in southwestern part of US
Coccidioidomycosis
______ histoplasmosis
miliary
pneumonia (miliary TB) due to _______ spread
hematogenous
pneumonia (miliary TB)
this type of spread is worse at bases of lungs due to blood flow being the greatest
hematogenous spread
hematogenous spread via septic emboli from ____
endocarditis
IV drug user
S. aureus on tricuspid valve
emboli breaks off into lungs
hematogenous spread of pneumonia from endocarditis
Histoplasma
Blastomyces
coccidioides
outpatient treatment for community acquired pneumonia
macrolide (azithromycin)
or
doxycycline
in patient treatment for community acquired pneumonia
cephalosporin (ceftriaxone) + macrolide (azithromycin)
S. pneumoniae
Haemophilus pneumoniae
Mycoplasma pneumoniae
Chlamydia pneumoniae
Influenza A and B
infection of pulmonary parenchyma
pneumonia
R sided chest pain worse with inspiration
pleuritic chest pain
pleuritic chest pain due to
inflammation of parietal pleura
S. pneumoniae
distinguishes strep from staph
catalase test
Catalase positive, Gram positive cocci
beta hemolytic
S. aureus
alpha hemolytic
Streptococcus
beta hemolytic
gram + diplococci
group A strep
virulence factor of S. pneumoniae
Pneumolysin
virulence factor of S. pneumonia that causes host cell damage and allows bacteria to invade host cell
Pneumolysin
Alveolar macrophages ruined by influenza A virus, can get post-viral infection with ______
S. pneumoniae
at risk for S. pneumoniae infection of lower resp. tract
smokers
alcoholics
post-viral infection
infection or no infection if S. pneumoniae colonizes upper respiratory tract
no infection
infection or no infection if S. pneumoniae is aspirated into lower resp. tract
infection
vaccine for S. pneumoniae that is not protein conjugated and does not protect children against invasive disease
Pneumococcal polysaccharide vaccine (PPS-23)
vaccine for S. pneumoniae that is protein conjugated and does protect children against invasive disease
Pneumococcal conjugate vaccine (PCV-13)
route of entry for S. pneumoniae infection
aspiration
S. pneumoniae
Haemophilus influenzae (pneumoniae)
gram - rod
catalase +
grows on chocolate agar
oxidase +
Haemophillus (influenza) pneumoniae
encapsulated
type b most pathogenic
Haemophilus influenzae (pneumoniae)
can cause meningitis in kids
Haemophilus influenzae (pneumoniae) type b
encapsulated and resists phagocytosis (PRP)
Haemophilus pneumoniae
causes bronchopneumonia and route of entry is through aspiration
H. influenzae causing Haemophilus pneumoniae
H. pneumoniae vaccine
for type b
conjugated
no cell wall
not seen on gram stain
causes interstitial pneumonia
Mycoplasma pneumoniae
specialized attachment tips
binds to cilia
Mycoplasma pneumoniae
spread by close contact
young people
no vaccine
Mycoplasma pneumoniae
diagnose this through cold Agglutins (IgM antibodies that bind to RBC at low temperature)
Mycoplasma pneumoniae
transmitted by inhalation from human to human
Mycoplasma pneumoniae
obligate intracellular
no vaccine
human to human spread (inhalation)
Chlamydia pneumoniae
-ssRNA enveloped virus
Influenza A and B
found in animals; humans
genetically unstable
Influenza A
infects only humans; URT
Influenza B
has membrane envelope proteins HA, NA, and M2
Influenza A
_____ binds sialic acid on host cells and allows for virus entry
HA proteins
____ cleaves sialic acid and releases virions
NA protein
acute
rhinitis
fevers
winter time
Influenza A
Interferon-gamma produced by T cells to control viral infection decreases alveolar macrophage phagocytic function
Suspected reason for the increase in secondary bacterial infections that are a major cause of death following initial infection
Influenza A
Due to small mutations in the regions of HA or NA that bind antibodies.
Due to Error-prone RNA polymerase
antigenic drift of Influenza A
re-assortment of genomes from 2 different flu strains
associated with major epidemics
Influenza A: antigenic shift
2 strains of Influenza A and 2 strains of B circulating over past year
Given IM
Recommended for everyone
killed Influenza A vaccine
nasal
not for immunocompromised
Live Attenuated Influenza A Vaccine