Fouty-Oxygenation

Question 1

oxygen content of blood (CaO2) units

Answer 1

ml O2/dL blood

Question 2

oxygen delivery (DO2) units

Answer 2

ml O2/min

Question 3

oxygen consumption (VO2) units

Answer 3

ml O2/min

Question 4

higher the altitude, lower the what

Answer 4

pressure (atmospheric)

Question 5

% of oxygen in atmosphere at sea level

Answer 5

21%

Question 6

PO2 at sea level

Answer 6

160 mmHg

Question 7

Pb (atmospheric pressure)

Answer 7

760 mmHg

Question 8

what stays the same when you are on a plane

Answer 8

nitrogen and oxygen % in the air (the concentration)

Question 9

what changes when you are on a plane

Answer 9

partial pressure of nitrogen and oxygen (due to atmospheric pressure decreasing)

Question 10

Answer 10

Patmosphere

Question 11

Answer 11

PiO2 (air gets humidified in upper trachea)

Question 12

Answer 12

PAO2 (CO2 here due to alveolar/capillary membrane)

Question 13

partial pressure of O2 in capillary is _______ to partial pressure of O2 in alveolus

Answer 13

identical

Question 14

in a normal person, O2 ___ happens rapidly

Answer 14

diffusion and equilibration of PO2 in capillary bed

Question 15

why is partial pressure of arterial O2 less than capillary and alveolus

Answer 15

b/c venous blood dumps into veins into LA (pulmonary + bronchial) —-mixed oxygenated

Question 16

PvO2

Answer 16

40 mmHg (tissue extraction of O2 occurred)

Question 17

oxygen dissolved in blood is solely dependent on _____

Answer 17

PO2

Question 18

normal CO

Answer 18

5L/min

Question 19

majority of oxygen for metabolism is carried by _____

Answer 19

Hb

Question 20

what to think when there is a curve that maxes out at P50 (partial pressure at which Hb is 50% saturated with O2)

Answer 20

CO poisoning

Question 21

ScO2

Answer 21

98%

Question 22

SaO2

Answer 22

97%

Question 23

SvO2

Answer 23

70%

Question 24

____ binding increases Hb affinity for subsequent O2 molecules

Answer 24

oxygen

Question 25

range of pressures when saturation and partial pressure of O2 are relatively linear

Answer 25

20-60 mmHg

Question 26

red curve green curve

Answer 26

red: advantage of tissue (Bohr effect) green: advantage of lung (Haldane effect)

Question 27

exercising causes what

Answer 27

right shift of curve (increase in CO2 from tissues and decrease in pH and increase in temp.)

Question 28

fever shifts curve where

Answer 28

right

Question 29

acidosis shifts curve where

Answer 29

right

Question 30

hypercarbia shifts curve where

Answer 30

right

Question 31

has stronger affinity for Hb than O2

Answer 31

CO

Question 32

decreases Hb saturation of O2 and decreases O2 content

Answer 32

CO

Question 33

low SaO2 due to what 3 things

Answer 33

decreased PaO2 R shift of curve abnormal hemoglobin

Question 34

how many mL in a dL

Answer 34

100 mL

Question 35

Answer 35

PvO2

Question 36

Answer 36

PcO2

Question 37

Answer 37

PaO2

Question 38

most O2 goes through the blood how

Answer 38

bound to Hb

Question 39

what mostly determines O2 content

Answer 39

SaO2, NOT PaO2

Question 40

CaO2 mostly determined by

Answer 40

Hb (g/dL) oxygen saturation (%)

Question 41

normal Hb

Answer 41

15

Question 42

Hb of 20

Answer 42

polycythemia

Question 43

Hb of 10

Answer 43

anemia

Question 44

DO2=

Answer 44

CO x CaO2

Question 45

normal DO2

Answer 45

1000 ml O2/min

Question 46

2 things that can increase CO to improve DO2

Answer 46

doputamine (ionotrope---increase contractility) IV fluid

Question 47

what can you do to increase Hb to improve DO2

Answer 47

transfusion

Question 48

if SaO2 is lower than you want, what can you do to improve it and improve DO2

Answer 48

give supplemental O2

Question 49

how can you increase partial pressure of O2

Answer 49

hyperbaric O2

Question 50

VO2=

Answer 50

CO x (CaO2-CvO2)

Question 51

normal VO2

Answer 51

250 ml O2/min

Question 52

consume about _____ of O2 that is being delivered

Answer 52

1/4th

Question 53

decrease in CO leads to tissue ____

Answer 53

hypoxia

Question 54

adequate tissue oxygenation dependent on what 2 things

Answer 54

content of O2 flow (of blood)

Question 55

binds O2 at very low partial pressures in the muscles

Answer 55

myoglobin

Question 56

____ acts at cytochrome C oxidase to accept electrons

Answer 56

oxygen

Question 57

low arterial O2

Answer 57

hypoxemic hypoxia

Question 58

oxygen affinity hypoxia due to what 3 things

Answer 58

CO poisoning methemoglobin massive transfusion

Question 59

low content of O2 due to what

Answer 59

anemic hypoxia

Question 60

inadequate oxygen delivery due to what

Answer 60

circulatory hypoxia (lactic acidosis)

Question 61

blocks O2 binding to cytochrome C oxidase causing histologic hypoxia

Answer 61

Cyanide

Question 62

delivery of O2 is normal but metabolism isn't (what type of lactic acidosis)

Answer 62

type B lactic acidosis

Question 63

O2 not getting to tissue for metabolism (type of lactic acidosis)

Answer 63

type A

Question 64

occurs when O2 not present to accept electrons

Answer 64

lactic acidosis

Question 65

usual response to inadequate oxygen delivery

Answer 65

lactic acidosis