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RES Biweekly 3 > Fouty-Oxygenation > Flashcards

Fouty-Oxygenation Flashcards

1
Q

oxygen content of blood (CaO2) units

A

ml O2/dL blood

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2
Q

oxygen delivery (DO2) units

A

ml O2/min

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3
Q

oxygen consumption (VO2) units

A

ml O2/min

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4
Q

higher the altitude, lower the what

A

pressure (atmospheric)

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5
Q

% of oxygen in atmosphere at sea level

A

21%

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6
Q

PO2 at sea level

A

160 mmHg

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7
Q

Pb (atmospheric pressure)

A

760 mmHg

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8
Q

what stays the same when you are on a plane

A

nitrogen and oxygen % in the air (the concentration)

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9
Q

what changes when you are on a plane

A

partial pressure of nitrogen and oxygen (due to atmospheric pressure decreasing)

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10
Q
A

Patmosphere

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11
Q
A

PiO2 (air gets humidified in upper trachea)

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12
Q
A

PAO2 (CO2 here due to alveolar/capillary membrane)

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13
Q

partial pressure of O2 in capillary is _______ to partial pressure of O2 in alveolus

A

identical

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14
Q

in a normal person, O2 ___ happens rapidly

A

diffusion and equilibration of PO2 in capillary bed

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15
Q

why is partial pressure of arterial O2 less than capillary and alveolus

A

b/c venous blood dumps into veins into LA (pulmonary + bronchial) —-mixed oxygenated

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16
Q

PvO2

A

40 mmHg (tissue extraction of O2 occurred)

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17
Q

oxygen dissolved in blood is solely dependent on _____

A

PO2

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18
Q

normal CO

A

5L/min

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19
Q

majority of oxygen for metabolism is carried by _____

A

Hb

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20
Q

what to think when there is a curve that maxes out at P50 (partial pressure at which Hb is 50% saturated with O2)

A

CO poisoning

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21
Q

ScO2

A

98%

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22
Q

SaO2

A

97%

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23
Q

SvO2

A

70%

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24
Q

____ binding increases Hb affinity for subsequent O2 molecules

A

oxygen

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25
Q

range of pressures when saturation and partial pressure of O2 are relatively linear

A

20-60 mmHg

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26
Q

red curve
green curve

A

red: advantage of tissue (Bohr effect)
green: advantage of lung (Haldane effect)

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27
Q

exercising causes what

A

right shift of curve
(increase in CO2 from tissues and decrease in pH and increase in temp.)

28
Q

fever shifts curve where

A

right

29
Q

acidosis shifts curve where

A

right

30
Q

hypercarbia shifts curve where

A

right

31
Q

has stronger affinity for Hb than O2

A

CO

32
Q

decreases Hb saturation of O2 and decreases O2 content

A

CO

33
Q

low SaO2 due to what 3 things

A

decreased PaO2
R shift of curve
abnormal hemoglobin

34
Q

how many mL in a dL

A

100 mL

35
Q
A

PvO2

36
Q
A

PcO2

37
Q
A

PaO2

38
Q

most O2 goes through the blood how

A

bound to Hb

39
Q

what mostly determines O2 content

A

SaO2, NOT PaO2

40
Q

CaO2 mostly determined by

A

Hb (g/dL)
oxygen saturation (%)

41
Q

normal Hb

A

15

42
Q

Hb of 20

A

polycythemia

43
Q

Hb of 10

A

anemia

44
Q

DO2=

A

CO x CaO2

45
Q

normal DO2

A

1000 ml O2/min

46
Q

2 things that can increase CO to improve DO2

A

doputamine (ionotrope—increase contractility)
IV fluid

47
Q

what can you do to increase Hb to improve DO2

A

transfusion

48
Q

if SaO2 is lower than you want, what can you do to improve it and improve DO2

A

give supplemental O2

49
Q

how can you increase partial pressure of O2

A

hyperbaric O2

50
Q

VO2=

A

CO x (CaO2-CvO2)

51
Q

normal VO2

A

250 ml O2/min

52
Q

consume about _____ of O2 that is being delivered

A

1/4th

53
Q

decrease in CO leads to tissue ____

A

hypoxia

54
Q

adequate tissue oxygenation dependent on what 2 things

A

content of O2
flow (of blood)

55
Q

binds O2 at very low partial pressures in the muscles

A

myoglobin

56
Q

____ acts at cytochrome C oxidase to accept electrons

A

oxygen

57
Q

low arterial O2

A

hypoxemic hypoxia

58
Q

oxygen affinity hypoxia due to what 3 things

A

CO poisoning
methemoglobin
massive transfusion

59
Q

low content of O2 due to what

A

anemic hypoxia

60
Q

inadequate oxygen delivery due to what

A

circulatory hypoxia (lactic acidosis)

61
Q

blocks O2 binding to cytochrome C oxidase causing histologic hypoxia

A

Cyanide

62
Q

delivery of O2 is normal but metabolism isn’t (what type of lactic acidosis)

A

type B lactic acidosis

63
Q

O2 not getting to tissue for metabolism (type of lactic acidosis)

A

type A

64
Q

occurs when O2 not present to accept electrons

A

lactic acidosis

65
Q

usual response to inadequate oxygen delivery

A

lactic acidosis

RES Biweekly 3 (11 decks)

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