Foundations in Immunology Flashcards
What cells are involved in innate immunity?
MAcrophages
Neutrophils
What cells are involved in adaptive immunity?
Lymphocytes
What are the 3 sectors of the immune system?
- Physical Barriers
- Phagocytic Cells
- Soluble factors
What physical barriers are part of the innate immune system?
- Tight junctions between epithelia
- Mucous Membranes
What occurs to neutrophils after phagocytosing?
They DIE!
What are the primary lympoid organs?
- Thymus
- Bone marrow
- Foetal Liver
Whats the function of primary lymphoid organs?
Producing & maturing lymphocytes
Whats the function of secondary lymphoid tissues?
Maintaining lymphocytes
Filtering lymph
Initiating immune responses
Where are some secondary lymphoid tissues?
- Lymph Nodes
- Spleen
What are the fundamental properties of the adaptive immune system?
- Specificity
- Diversity
- Memory
- Recruitment of other defence mechanisms
What do B cells differnetiatie to?
PLasma cells
What do palsma cells do?
Synthesise antibodies
What part of an antibody binds to the antigen?
Antibody paratope binds to antigen epitope
What are antigens?
Proteins able to evoke an immune response by reactin with immune products
How many serum proteins make yp the complement sustem?
25