Forces of Protein folding--stability

Question 1

what is affisen’s dogma?

Answer 1

aka thermodynamic hypothesis; tertiary structure is determined by primary structure (for at least small globular proteins); denaturing a protein causes it to lose its catalytic activity

Question 2

transient chemical interactions form the basis of biochemistry and life itself

Answer 2

ya

Question 3

where are disulfide bonds found?

Answer 3

in non-reducing enviros–>in the ECF or on the EC side of the membrane; uncommon in proks but exist when proks are in harsh conditions (extremophiles)

Question 4

e of interaction eqn

Answer 4

k x q1q2/er