S. aureus
G+ cocci; grape-like clusters
catalase + (diff from strep)
coag + (diff from other staph)
beta hemolytic
S. aureus virulence
enterotoxin (serotypes A-D) heat stable resistant to acidity and gast enzymes stim peristalsis stim vomiting can stim TSS and mediate cytokine storm
S. aureus food poisoning
1-6hrs after eating
N/V/D/sweating/headache/cramps
watery and nonbloody diarrhea
antibios not indicated
Bacillus cereus
G+ rod spore-forming resist to dry heat and chemical changes grains including rice esp reheated rice (spores germinate when warmed)
B. cereus food poisoning
emetic --> 4hrs heat stable enterotoxin contaminated rice self limiting diarrheal --> 24hrs resembes clostridial gastroenteritis heat labile toxin --> inc cAMP contam meat, veggies, gravies self limiting
Clostridium botulinum
G+ rod obligate anaerobe spore-forming found in soli, ponds and such home canning and home smoked fish honey w/ newborns
C. botulinum virulence
neurotoxic exotoxin –> prev ACh release –> flaccid paralysis
C. botulinum food poisoning
Food --> preformed toxin ingestion descending paralysis with other Sx Wound --> lack GI Sx Infantile --> honey with spores; most common form in US antibio not recommended