Aseptic Meningitis and Encephalitis

Question 1

Naegleria fowleri

Answer 1

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Question 2

Leptospira interrogans

Answer 2

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Question 3

Enteroviruses (Polio, Coxsackie, Echovirus)

Answer 3

non-env ss+ RNA
virus genome serves as own mRNA; post-xslational modifications
Xsmit via fecal-oral route
NO animal reserve
late summer, early fall

Question 4

Poliovirus patho

Answer 4

colonizes epith and lymph cells of pharynx, and Peyer’s patches in intestine
90% are asymptomatic
can also cause flu, aseptic meningitis, and paralytic dz
dest of ant horn cells (bulbar polio)–> death due to resp failure
Sabine vaccine –> live attenuated
Salk –> killed; used in US

Question 5

Coxsackievirus A

Answer 5

hand, foot, mouth disease
herpangina –> herpes-like vesicles in buccal mucosa
common cause of aseptic meningitis
note that Group B is assoc with myo and pericardial infections

Question 6

Echovirus

Answer 6

leading cause of viral meningitis
maculopapular, petechial, or vesicular rash
Dx with PCR (all enteroviruses)

Question 7

Dengue virus

Answer 7

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Question 8

Rabies virus

Answer 8

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Question 9

Lassa virus

Answer 9

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Question 10

Ebola virus

Answer 10

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Question 11

Hanta virus

Answer 11

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