FM 3 Misc

Question 1

typical CSF findings in acute bacterial meningitis (9)

Answer 1

1. elev opening P (>180 mmH2O)
2. high WBC (1000-5000)
3. lots of PMNs
4. high protein (100-500)
5. low glucose (<40 mg/dl)
6. gram stain + in 60-90%
7. • culture in 70-85%
8. bacterial Ag test in 50-100%
9. PCR helpful but time consuming

Question 2

what is the most common type of HIV in North America?

Answer 2

HIV-1, Group M, subtype B

Question 3

HIV-2

Answer 3

West Africa, SE Asia, India, Portugal, parts of Europe
very closely related to SIV
slower progression of immunodeficiency than HIV-1

Question 4

HIV genes for proteins

Answer 4

Pol: encodes reverse transcriptase, protease, integrase *impt targets for antiretroviral meds
Env: polypeptide that is cleaved to form gp120 and gp41 on viral envelope, needed for attachment to and fusion w/ CD4 cells
Gag: proteins that make up viral core

Question 5

Bartonella infection in pts w/ AIDS (10)

Answer 5

Bacillary angiomatosis
Peliosis hepatis
Hepatitis
Splenitis
Endocarditis
Osteomyelitis
Uveitis *HLA-B27
Prolonged bacteremia and persistent fevers
Breast abscess
Neuro manifestations