Anaerobic Inf

Question 1

mechanisms by which anaerobes cause disease (3)

Answer 1

1. mucosal barrier disruption
2. devitalized tissue –> creation of micro-anaerobic environments
3. toxin *clostridia

Question 2

clinical risk factors for anaerobic inf (9)

Answer 2

1. malig
2. occlusion of airway
3. occlusion of vessel
4. vascular disease
5. DM
6. trauma
7. immune compromise
8. foreign bodies
9. Abx pressure ineffective against anaerobes

Question 3

bactericides fragilis

Answer 3

GI
hallmark is abscess formation
increasing drug resistance to clindamycin and beta-lactams

Question 4

bacteriodes

Answer 4

mouth, GU

Question 5

fusobacterium

Answer 5

long, thin, fusiform (pointed ends)
mouth, gingivae
produce endotoxin

Question 6

peptostreptococci

Answer 6

mixed flora infections

Question 7

anaerobes in the oral cavity (5)

Answer 7

peptostreptococcus
prevotella
fusobacterium
bactericides (not b fragilis)
actinomyces

Question 8

anaerobes in GI tract (4)

Answer 8

bacteriodes fragilis
peptostreptococcus
fusobacterium
clostridia

Question 9

anaerobes in female GU tract (4(

Answer 9

prevotella
peptostreptocus
bacteriodes fragilis
clostridia