Fiser ABSITE Ch. 35 Small Intestine Flashcards
Function of: Small intestine? Large intestine?
Nutrient and water absorption; Water absorption
Duodenum anatomy: -Retroperitoneal portions? -Vascular supply?
-2nd and 3rd -Superior (off GDA) and inferior (off SMA) pancreaticoduodenal arteries
Jejunum: -Anatomy? -Function?
-100 cm long, long vasa recta, supplied by SMA -90% of water, 95% NaCl absorption
Ileum: -Anatomy -Function
-150 cm, short vasa recta, SMA supply -B12, folate and bile acid absorption
Short gut syndrome: -Diagnostic tests -Treatment
-Sudan red (fecal fat) -Schilling test (radiolabeled B12) -Fat restriction, PPI, lomotil
How much small bowel needed to survive with TPN in short gut?
75 cm or 50 cm with competent ileocecal valve; Meckel’s diverticulum (rule of 2’s)//2 FEET from ileocecal valve; 2 years old; 2% of population; 2 types of tissue (pancreatic, gastric)
How does Meckel’s present?
Bleeding in children. Obstruction in adults.
Segmental resection in Meckel’s?
-Neck > 1/3 of luminal diameter -Complicated diverticulitis -Diverticulitis involves base
Perianal disease in Crohn’s:
-First presentation in 5% -Presents as SKIN TAGS -Treat with FLAGYL
Medical treatment of Crohn’s
-Loperamide and 5-ASA -Steroids for acute flares -anti-TNF-alpha inhibitors for steroid-resistant or fistulas; 90% will need surgery
What cell type produces serotonin?
Kulchitsky (enterochromaffin) cells
Serotonin metabolism
Part of the amine precursor uptake decarboxylase (APUD) system. 5-HIAA is a breakdown product that can be measured in urine.
Carcinoid tumors release:
NAME?
Symptoms of carcinoid syndrome and treatment:
NAME?
Detection and localization of carcinoid?
Detect - Chromogranin A level; Localize - Octreotide scan