Fiser ABSITE Ch. 25 Thoracic Flashcards
What is the position of the phrenic nerve and vagus nerve in the hilum?
■ Phrenic nerve - runs anterior to hilum
■ Vagus nerve - runs posterior to hilum
What percentage of total lung volume is from the right lung?
55%
What percentage of quiet inspiration is from the diaphragm? and the intercostals?
80%, 20%
Which pneumocytes produce surfactant?
Type II
What structures direct air exchange between alveoli?
Pores of Kahn
How much pleural fluid is produced per day?
1-2 L
Which layer of the pleura produces pleural fluid and which layer has the lymphatics that clear the fluid?
parietal pleura produces pleural fluid cleared by lymphatics in the visceral pleura
What is the most common single site of lung CA mets?
brain
What is the overall 5 year survival rate for lung CA? and with resection?
10%, 30%
What is the most common type of lung CA?
adenocarcinoma
Local recurrence is increased with which type of lung CA? and distant metastases?
local recurrence, distant metastases
What percentage of pts with small carcinoma are surgical candidates?
Less than 5% (most get just chemo and XRT)
What is the most common paraneoplastic syndrome?
Small cell ACTH
What is the most malignant lung tumor?
mesothelioma
Name two chemotherapy agents used for small cell lung CA
cisplatin, etopside
What is the name of the procedure used to assess aortopulmonary window nodes; goes through left 2nd rib cartilage?
Chamberlain procedure
In addition to Horner’s syndrome, what other nerve can have sx with Pancoast tumor?
ulnar
Coin lesions are overall 5-10% malignant. Age 50?
Less than 5%, 50%
What type of tumor is carcinoids? what is the tx?
neuroendocrine, tx: resection; treat like CA
Name the lung mass:
• Submucosal glands; spread along perineural lymphatics, well beyond endoluminal component; XRT sensitive • Slow growing; can get 10-year survival with incomplete resection • Tx: resection; if unresectable, XRT can provide good palliation
Adenoid cystic adenoma, Thyroid CA and goiters, T-cell lymphoma, Teratoma, Parathyroid adenomas
What is the tx for all thymomas?
resection
What is the tx for mediastinal teratoma? and seminoma?
resection and chemo for teratoma; seminoma is very XRT sensitive, chemo for positive nodes or residual disease; surgery for residual disease after that
90% of nonseminoma mediastinal germ cell tumor have elevations in what two markers? and what is the tx?
beta-HCG and alpha-fetoprotein
Tx: cisplatin-based chemo and XRT; surgery for residual disease