Fischer Lab Procedure Flashcards
Add a half scoop of … to a … mL Rb Fk
molecular sieves; 50
50 mL Rb Fk should have a …
blue magnetic stirbar
To 50 mL Rb Fk, add … mL of …, and … mL of … and add … drops of …, dropwise, swirling after each drop
5.4; 3-methyl-1-butanol; 5.7; glacial acetic acid; 6; H2SO4
At hood, set up …, with a … on top of the drying tube, Reaction vessel in reflux should be …
reflux; drying tube; foil tented
Set heat to about
8
Reflux for …
one hour
Once reflux is done, cool to …. Unplug variac, turn the heat to zero, and lower the heating mantle. After cooling to room T, put … and raise jack to immerse beaker
room temp; ice bath
ice bath should be in a … mL beaker
250
set up … over a 100 mL empty beaker and insert a … on the top
separatory funnel; glass funnel
dilute a solution of 5% NaHCO3 to … % by adding … ml of … and .. mL of … This mixture should also be cooled in an … and should be added to a … mL …
2.5; 20; NaHCO3; 20; H2O; ice bath; 50; beaker
Obtain … mL of pentane in a …. mL … Cork this Fk after obtaining pentane
28; 25; E. Fk
Add about .. mL pentane to Rb Fk while its still in ice bath
20
After Rb Fk is ice cold (after about .. min) remove beaker and dismount condenser and drying tube
5
Pour the 40 mL NaHCO3 solution into the separatory funnel via the … and then add the … …
glass funnel; rxn mixture dropwise
To mix the contents in separatory funnel, do not …, but use … to stir
shake; spatula
Drain aqueous layer (lower layer) from separatory funnel into the … mL … that contained the …
50; beaker; NaHCO3
Drop pentane layer from top into a .. mL …
125; E. Fk
Extract a second time by adding … back into separatory funnel and adding an additional … mL pentane
aqueous layer; 10
In E. Fk containing extracted organic layer, add …
Na2SO4
When organic layer is dry, transfer to a … mL … via a … Seal Rb. Fk with … and … and store
100; Rb. Fk; gravity filtration; Teflon stopper; parafilm
At next lab, set up a …
semimicro distillation
Distill pentane into a rubber-banded … mL Rb Fk
50;
Receiving flask for semimicro distillation should be condensed over a … mL … filled with …
250; beaker; ice
Distill pentane until temp starts rising, then …
switch receiving flask
receiving flask for ester should be a … and should also be placed over
25 mL Rb Fk; ice bath
when done distilling determine …, …., and …
weight; IR; RI
