First Exam; Practice Exam Flashcards
What hormones bind to intracellular receptors?
Steroids
List the events of cAMP in order
Alpha subunit binds to adenylyl cyclase, cAMP is produced, cAMP binds to protein kinase, phosphate groups are attached to enzymes, phosphodiesterase breaks down cAMP
Name four different second messengers
cAMP, DAG, IP3, and CGMP
When is a G protein active?
When GTP is bound to it
The cholera toxin doesn’t allow GTP to be hydrolyzed to GDP. What effects would you expect to see in the cell?
The activated G proteins would remain locked in the “on” position, transmitting signal even in the absence of a signaling molecule
What converts ATP to cyclic AMP?
Adenylate Cyclase
What event would activate a G protein?
The replacement of GDP with GTP
Cholera develops when the bacterial toxin _______________
prevents G-protein inactivation, which leads to the continuous production of cAMP
During the transduction of a signal, one molecule or ion may be closely associated or interact with the activity of another. What are 4 examples of correctly combined molecules?
Calcium-IP3, cAMP-adenylyl cyclase, cAMP-protein kinase A, and DAG-IP3
What’s the difference between the mechanisms of cAMP and Ca2+ in signal transduction?
cAMP is synthesized by an enzyme in response to a signal, and Ca2+ is released from intracellular stores
What is IP3 produced as a result of?
IP3 is produced as a result of protein kinase A activation
What does IP3 do?
It opens CA2+ channels
What is the general name for an enzyme that transfers phosphate groups from ATP to a protein?
Protein kinase
What do G protein coupled receptors rely on? Examples?
G protein coupled receptors rely on second messengers such as Ca2+, cAMP, phosphatidylinositol, and cGMP to activate or inactivate a variety of pathways within the cell.
In an endothermic reaction, is the chemical potential energy lower in the reactants than in the products?
Yes
What is true of an endergonic reaction?
The reaction isn’t spontaneous and is accompanied by an increase in Gibb’s free energy (🔺G > 0), and the value of 🔺G provides a measure of the amount of free energy needed to drive the reaction
Define work
When energy is transferred from one body place to another
What is bond energy measured in? What two things is it equal to?
Bond energy is measured in kJ, and is equal to the minimum energy required to break one of the bonds between two types of atoms. It’s also equal to the amount of energy released when a bond is formed
Name 5 ways in which entropy can increase during a chemical reaction
- Liquid reactants become gaseous products, 2. Solutes move from an area of high concentration to an area of low concentration until they’re uniformly distributed in the volume 3. complex molecules react to form simpler molecules, 4. fewer molecules of reactant molecules form a greater number of moles of product molecules, and 5. solid reactants become liquid or gaseous products
Most of the reactions of metabolism are a series of chain reactions in which the product of one reaction is the reactant of another reaction. What happens to the final product of the chain?
It’s released into the external environment
What does the second law of thermodynamics state?
That the entropy of the universe increases with any change that occurs
True or false: Living things build up their bodies and the world around them. They do this at the expense of the entropy of the universe as a whole.
True
Define Gibbs free energy
Energy that can do useful work
True or false: The free energy release of ~54kJ/mol in a living cell ATP reaction makes it a relatively poor source of energy for driving endergonic processes in the cell
False
True or false: A cell whose reversible reactions have reached equilibrium is a living cell.
False
A diver jumps off a diving tower. When will the diver have the highest kinetic energy?
Just when the diver approaches the water
The substance that loses the electron is oxidized, and then the substance that takes the electron is called the ______ agent
Oxidizing
Adenosine triphosphate is the secondary source of free energy in living cells
False
Define a catabolic reaction
A reaction that results in the breakdown of complex substances
What does the first law of thermodynamics state?
That the total amount of energy in the universe is constant, and that if an object/process gains an amount of energy it does so at the expense of a loss in energy somewhere else in the universe