FINALS: Opistorchis species (Liver Flukes) Flashcards

1
Q

“Southeast Asian liver fluke”

A

Opistorchis viverrini

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2
Q

“cat liver fluke”

A

Opistorchis felineus

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3
Q

Definitive host:

A

cats, dogs, other fisheating mammals

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4
Q

Intermediate host:
1st snail

A

Bithynia

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5
Q

2nd: freshwater fish

A

Cyprinidae
Cobitidae

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6
Q

Infective Stage:

A

metacercariae

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7
Q

Diagnostic Stage:

A

embryonated egg

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8
Q

• Operculated with prominent shoulders
• Has an abopercular knob
• Shell: thick rim
• Content: well-developed miracidium

A

Egg

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9
Q

• Testes: lobate, arranged obliquely
• O. viverrini: closer to each other and more deeply lobulated

A

Adult Worm

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10
Q

coser to each other and more deeply lobulated

A

O. viverrini

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11
Q

Opistorchis viverrini
o Symptoms: flatulence, fatigue,
dyspepsia, pain in the upper right quadrant of the abdomen, anorexia, and mild hepatomegaly

A

Light infection

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12
Q

Opistorchis viverrini
o Symptoms: obstructive jaundice, cirrhosis, cholangitis, and acalculous cholecystitis or bile peritonitis

A

Severe infection

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13
Q

Opistorchis felineus

o Symptoms: fever and hepatitis-like symptoms

A

Acute phase

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14
Q

Opistorchis felineus
o Symptoms: biliary tract obstruction, inflammation, fibrosis, liver abscess formation, pancreatitis, and suppurative cholangitis

A

Chronic phase

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15
Q

most serious complication for O. viverrini

A

Cholangiocarcinoma

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16
Q

DIAGNOSIS

A

• Detection of eggs in stool
• Cholangiography
• ELISA, EIA
• Coproovoscopy
• PCR

17
Q

• Praziquantel: 25 mg/kg thrice a day for 2 days o 60 mg/kg in 3 doses for one day
• Albendazole: alternative drug • Praziquantel-albendazole combination
• Tribendimidine

A

Treatment