FINALS: LUNG TREMATODE Flashcards

1
Q

“Oriental lung fluke”

A

Paragonimus westermani

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2
Q

Causes 90% of paragonimiasis in Asia

A

Paragonimus westermani

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3
Q

identified in cats

A

P. siamensis

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4
Q

Definitive host:

A

humans

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5
Q

Intermediate host:
o 1st

A

▪ Antemelania asperata
▪ Antemelania dactylus (formerly known as Brotia asperata)

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6
Q

formerly known as Brotia asperata

A

Antemelania dactylus

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7
Q

2nd
▪ Mountain crab:

A

Sundathelphusa philippina (formerly known as Parathelphusa grapsoides)

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8
Q

formerly known as Parathelphusa grapsoides

A

Sundathelphusa philippina

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9
Q

Infective Stage:

A

metacercariae

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10
Q

Diagnostic Stage:

A

unembryonated egg

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11
Q

EGGS
Shape

A

Somewhat oval

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12
Q

chronic bronchiectasis and pleural fibrosis, secondary-severe parenchymal and pleural damage

A

Sequelae

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13
Q

cause both pulmonary and ectopic paragonimiasis

A

Heavy intensity infections

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14
Q

releases IgE, resulting to an allergic reaction

A

Peritoneal macrophage

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15
Q

releases protease, resulting to eosinophil-associated tissue inflammation

A

Metacercariae

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16
Q

Paragonimiasis
• Most common symptoms:

A

chronic cough and hemoptysis

17
Q

Cutaneous and cerebral paragonimiasis:

A

classic forms of ectopic infection

18
Q

feature: slow-moving, nodular lesion in the subcutaneous tissue on the abdomen or chest

A

Cutaneous paragonimiasis

19
Q

most serious complication of human paragonimiasis
o Manifestations: headache, seizures, meningismus, hemiparesis, blurring of vision, diplopia, homonymous hemianopsia, and aphasia

A

Cerebral paragonimiasis

20
Q

detection of the characteristic eggs in sputum, stool, or in aspirated material from abscess or pleural effusions

A

Microscopy

21
Q

best sensitivity for microscopic diagnosis

A

Sputum concentration with 3% NaOH

22
Q

CT scan or MRI for cerebral paragonimiasis

A

Chest radiographs

23
Q

immunoblotting, ELISA

A

Serology

24
Q

epidemiological surveys in developing countries

A

Loop-mediated isothermal amplification (LAMP) test

25
Q

alternative drug

A

Bithionol

26
Q

binds to B-tubulins = depolymerization and disruption of microtubule-based processes

A

Triclabendazole