Final Exam - Respiratory System Flashcards
What are the three components of the respiratory system?
- Conductive system
- Transitional system
- Gas exchange system
These are thin-walled structures enveloped by a rich network of capillaries: the pulmonary capillaries.
alveoli
Identify.

alveoli
Identify the H&E section pictured here.

The respiratory portion of the nasal cavity
lined by ciliated pseudostratified columnar epithelium with goblet cells
What structure is indicated by the arrow in this H&E section of the nasal cavity?

tubulo-alveolar glands
mainly serous, with lesser numbers of mucous and mixed glands.
Which region of the nasal cavity is pictured here?

The vestibular region.
This is the initial, external part of the nasal cavity with cutaneous mucous membrane, hairs and skin glands. It is lined with stratified squamous keratinized epithelium
Goblet cells produce _________ granules.
Goblet cells produce mucinogen granules.
Identify the structures indicated by the arrows in this H&E section of the trachea

goblet cells
Identify the structures indicated by the arrows in this H&E section of the trachea

cilia
Identify the type of epithelium labeled ‘A’ in this H&E section of the nasal cavity

respiratory epithelium
Identify the type of epithelium labeled ‘B’ in this H&E section of the nasal cavity

olfactory epithelium
Located in the dorsal part of nasal cavity (olfactory region). Olfactory epithelium is much thicker than respiratory epithelium. NO GOBLET CELLS ARE PRESENT
Identify the structures indicated by the arrows in this H&E section of the olfactory region of the nasal cavity

swell bodies
Swell bodies are venous plexuses found in both olfactory and respiratory regions. Swell bodies are distended with blood.
Identify ‘A’ in this H&E section of the larynx

laryngopharynx
Identify ‘B’ in this H&E section of the larynx

thyroid cartilage
What tissue are we looking at in this image?

trachea
The trachea is lined by ciliated pseudostratified columnar epithelium. In the trachea, the lamina propria and the submucosa are not clearly demarcated. Serous glands are seen in the lamina propria/submucosa.
What are we looking at in this image?

trachea
rings of cartilage support the tracheal wall
a connective tissue adventitia completes the wall of the trachea
What type of cell is indicated by arrow A in this diagram of tracheal mucosa?

goblet cell
What type of cell is indicated by arrow B in this diagram of tracheal mucosa?

Ciliated cell
What is indicated by arrow C in this diagram of tracheal mucosa?

L. muscularis mucosae
What is indicated by arrow D in this diagram of tracheal mucosa?

Serous glands, loose CT vessels
What is indicated by arrow E in this diagram of tracheal mucosa?

Cartilage
What structure is indicated by arrow ‘A’ in this H&E section of the trachea?

goblet cell
What structure is indicated by arrow ‘B’ in this H&E section of the trachea?

cilia
What structure is indicated by arrow ‘C’ in this H&E section of the trachea?

basal cells
The trachea bifurcates into the ________, which enter the lung and branch extensively.
The trachea bifurcates into the bronchi, which enter the lung and branch extensively.
Bronchi are lined by what type of epithelium?
Bronchi are lined by ciliated pseudostratified columnar epithelium
What tissue are we looking at in this section?

bronchus
What are the structures indicated by the circle in this H&E section of the bronchus?

mixed bronchial glands
Smooth muscle surrounds the lamina propria followed externally by connective tissue containing mixed bronchial glands and plates of hyaline cartilage
What are the structures indicated by the arrow in this H&E section of the bronchus?

plate of hyaline cartilage
Smooth muscle surrounds the lamina propria followed externally by connective tissue containing mixed bronchial glands and plates of hyaline cartilage.
What is indicated by ‘A’ in this H&E section of the lung?

alveoli
What is indicated by ‘B’ in this H&E section of the lung?

cartilage
What is indicated by ‘C’ in this H&E section of the lung?

bronchus
What tissue are we looking at?

bronchioles
bronchi branch into bronchioles. Bronchioles lack cartilage and glands and are subdivided into terminal bronchioles and respiratory bronchioles.
Terminal bronchioles are lined by:
Terminal bronchioles are lined by ciliated cuboidal cells with few to no goblet cells
Where are clara cells located?
Clara cells are located in terminal and respiratory bronchioles
What are the cells indicated by the arrows in this H&E section of the lung?

clara cells
Clara cells bulge at the surface and are located in terminal & respiratory bronchioles
Respiratory bronchioles are lined by:
Respiratory bronchioles are lined by ciliated cuboidal epithelium (indicated by the arrow), which become flattened distally

Identify ‘A’ in this H&E section of the lung

respiratory bronchiole
Identify ‘B’ in this H&E section of the lung

Alveolus
Alveolar ducts are part of the exchange system and they empty into ____________
Alveolar ducts are part of the exchange system and they empty into alveolar sacs and alveoli.
The walls of alveolar ducts are composed entirely of alveoli lined with _________________
The walls of alveolar ducts are composed entirely of alveoli lined with simple squamous epithelial cells.
What are we looking at in this image?

alveolar ducts
Alveolar ducts branch into alveolar sacs which lack ____________
Alveolar ducts branch into alveolar sacs which lack smooth muscle
Alveoli are lined by two distinct epithelial cells: ___________ & ___________
Pneumocytes type I
&
Pneumocytes type II
What is indicated by the arrow in this H&E section of the alveolar ducts?

Pulmonary Edema:
Alveolar spaces filled with proteinaceous fluid
Pneumocyte Type I cell is also known as _____________.
Squamous Alveolar Type I cell
Pneumocyte Type I cells compose ___% of alveolar surface area
95%
What structure is indicated by arrow ‘A’ in this toluidine blue section of the lung?

continuous capillary
What is indicated by ‘B’ in this toluidine blue section of the lung?

alveolus
Pneumocyte Type II cells compose ___% of alveolar surface area
5%
Pneumocyte Type II cells are also known as _______________.
Granular Alveolar Type II cells
Pneumocyte Type II cells contain ______________, which secrete surfactant
lamellar bodies
_________ stimulates production of surfactant in fetus just prior to parturition
Cortisol
Absence of surfactant in newborns is know as ___________________.
Hyaline Membrane Disease
__________ functions to reduce surface tension, reducing effort needed to inflate alveoli, thus preventing alveolar collapse (known as Atelectasis)
Surfactant
What is indicated by 1?

Interalveolar Septum
What is indicated by 2?

Continuous capillary
What is indicated by 3?

endothelial cell
What is indicated by 4?

erythrocytes
What is indicated by 5?

Pneumocyte Type I
What is indicated by 6?

Cytoplasm of Type 1 cell
What is indicated by 7?

Pneumocyte Type II (Granular pneumocyte)
What is indicated by 8?

Collagenous fibrils
What is indicated by 9?

elastic fibers
The lungs are covered by the visceral pleural composed of connective tissue and lined by:
simple squamous epithelium (indicated by the arrow)

The pleura is composed of simple squamous epithelial cells also known as ___________.
mesothelial cells
The largest part of the nasal cavity is lined by pseudostratified columnar ciliated epithelium with goblet cells. This combination of cells is known as the ____________, responsible for clearance.
Mucociliary apparatus
