Final Exam - NSAIDs/Anti-Inflam Flashcards

1
Q

The nurse is taking care of patients taking ibuprofen. Which of the following should be included in her assessment?

A) BP & bowel sounds
B) Weight/appetite
C) Muscle strength & ROM
D) RR, depth, rhythm

A

A) BP & bowel sounds - b/c NSAIDs are associated with hypertension & GI upset. All other options are not relevant

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2
Q

Upon checking the med chart, the nurse found out that his patient is taking both acetaminophen & furosemide. Which of the following interventions is an appropriate nursing action for these two drugs?

A) Administer meds as they are b/c they enhance drug actions
B) Measure patient’s I/O closely
C) Arrange for SGPT monitoring
D) Assess for signs & symptoms of bleeding

A

B) Measure patient I/O closely - b/c Acetaminophen can decrease the diuretic effect of loop diuretics so it is important to monitor patient fluid retention

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3
Q

Which of the following patient manifests acetaminophen toxicity?

A) Marie, 26, w/ new-onset jaundice while on drug therapy
B) Eva, 54, w/ difficulty of breathing while on drug therapy
C) Steven, 37, w/ joint stiffness while on drug therapy
D) Robert, 29, w/ new-onset glaucoma while on drug therapy

A

A) Marie, 26, w/new-onset jaundice while on drug therapy

b/c Acetaminophen toxicity manifests as severe hepatotoxicity

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4
Q

Which enzyme is found in active sites of trauma or injury?

A) Streptokinase
B) COX-1
C) Alpha-ketoglutarate
D) COX-2

A

D) Cox-2

b/c The presence of this enzyme in active sites of trauma prompts increase in prostaglandins. NSAIDs block COX-2 before signs & symptoms of inflammation can develop

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5
Q

The patient asked the nurse of how soon pain relief will be achieved after a dose of IV NSAIDs. The nurse would be correct by answering:

A) 5-10 minutes depending on the site involved
B) At the start of the infusion
C) 30 minutes since pain is usually extensive
D) At the first hour of infusion

A

B) At the start of infusion

b/c onset of action of NSAIDs is immediately after infusion. In oral form, onset is 30 minutes after administration

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6
Q

Which of these lab values would indicate toxicity in a patient taking acetaminophen daily?

A) Direct bilirubin level of 2mg/dl
B) Platelet count of 400,000mm3
C) Sodium level of 140mEq/L
D)Prothrombin time of 12 seconds

A

A) Direct bilirubin level of 2mg/dl

B/C bilirubin level of 2mg/dL or greater indicates acetaminophen toxicity (hepatotoxicity)

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7
Q

Which of the following is an antidote for opioid overdose?

A) Flumazenil
B) Glucagon
C) Naloxone
D) N-acetylcysteine

A

C) Naloxone

B/C Naloxone is the antidote for opioid overdose by competitively binding to u-opioid receptors.

Flumazenil is an antidote to benzodiapines. Glucagon is an antidote for beta blocker overdose. N-acetylcysteine is an antidote for acetaminophen.

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8
Q

Which of the following OTC analgesics is one of the most common causes of liver failure in the USA?

A) Naproxen
B) Acetaminophen
C) Ibuprofen
D) Aspirin

A

B) Acetaminophen

B/C Acetaminophen in doses over 3000mg per day can result in significant liver damage or failure.

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