Final Exam GI Physiology: Exocrine Pancreas

Question 1

What are the functions of the pancreas?

Answer 1

To dilute and buffer chyme to create an optimal pH

Hydrolyze proteins, carbs, lipids, and nucleic acids

Question 2

What are the products of acinar cells?

Answer 2

Proteases- Trypsinogen, chymotrypsin, procarboxypeptidase
Pancreatic amylase
Pancreatic lipase

Less important: Cholesterolesterase, phospholipase, ribonuclease, deoxyribonuclease, electrolytes, GIF

Question 3

What cells increase the HCO3- content of pancreatic fluid?

Answer 3

Ductular cells

Question 4

What is acid tide?

Answer 4

Refers to the plasma leaving the pancreas

Question 5

What do ductular cells do with Na+ and K+?

Answer 5

They reabsorb Na+ and secrete K+

Question 6

The cephalic, gastric, and intestinal phases of the pancreas are all ___________.

Answer 6

Stimulatory

Question 7

What controls the cephalic phase of pancreatic acinar cell secretion?

Answer 7

Stimuli: Sensory, Thought, Swallowing

Question 8

What controls the gastric phase of pancreatic acinar cell secretion?

Answer 8

Gastrin and vagovagal reflex

Question 9

What controls the intestinal phase of pancreatic acinar cell secretion?

Answer 9

CCK!! and secretin

Question 10

What stimulates the vagovagal reflex?

Answer 10

H+, fat breakdown products, peptides, AAs

Question 11

What control pancreatic ductular cell secretion?

Answer 11

ACh, secretin, and CCK all INCREASE the secretion