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ENR Biweekly 1 > Fields- formation of male reproductive system > Flashcards

Fields- formation of male reproductive system Flashcards

1
Q

_____ develop in the yolk sac

A

germ cells

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2
Q

migrate to genital ridge (L1) where they develop into gametes (sperm)

A

germ cells

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3
Q

aggressive tumors; contains more than one cell type

A

non-seminomas

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4
Q

contains one cell type; highest cure rate at 95%

A

seminoma

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5
Q

3 major germ cell tumor markers

A

AFP, LDH, beta hCG

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6
Q

from intermediate mesoderm

A

gonads

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7
Q

intermediate mesoderm (genital ridge) to _____ gonad (genital ridge) at weeks 5-6

A

indifferent

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8
Q

responsible for testes formation; Y linked

A

SRY gene product (TDF: testis determining factor)

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9
Q

_______derived cells migrate into the intermediate mesoderm where the testes are forming

A

peritoneum

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10
Q

peritoneum derived cells form _____ around the germ cells

A

sex cords

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11
Q

derived from sex cords and is where sperm is being developed

A

seminiferous tubules

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12
Q

derived from sex cords and moves sperm to efferent ductules

A

Rete Testis

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13
Q

moves sperm to epididymis

A

efferent ductules

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14
Q

derived from peritoneum

A

rete testes
seminiferous tubule
sertoli cells

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15
Q

derived from fibroblast

A

Leydig cell

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16
Q

_____ tumors are the most common testicular tumors

A

germ cell tumors

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17
Q

Choriocarcinoma
Yolk Sac
Embryonal
Teratoma

A

types of germ cell tumors

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18
Q
A

germ cell tumor

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19
Q

Produces estrogen.
Produces Androgen Binding Protein;
binds and transports testosterone.
Produces Inhibin.
Mullerian Inhibiting Factor

A

Sertoli cell

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20
Q

produces testosterone
produces estradiol 17beta

A

Leydig cell

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20
Q
A
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21
Q

After age 40, testosterone levels decrease by 1% each year leading to ____

A

Andropause

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22
Q

2 ducts that form genital ridge

A

Mullerian and Wolffian

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23
Q

responsible for male sex organs

A

Wolffian duct

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24
Q

responsible for female sex organs

A

Mullerian duct

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25
Q
A

B.

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26
Q

duct that is mesonephric

A

Wolffian duct

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27
Q

duct that is paramesonephric

A

Mullerian duct

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28
Q

remnants of Mullerian(paramesonephric) duct in males

A

appendix testis
prostatic utricle
uterovaginal primordium

29
Q
A

appendix testis

30
Q

associated with:
Low Mullerine Inhibiting Factor (MIF) from sertoli cells
Resistance to MIF

A

enlarged prostatic utricle

31
Q

responsible for formation of Wolffian duct

A

testosterone

32
Q

mesonephric duct remnant

A

appendix epididymis

33
Q

mesonephric duct remnant

A

paradidymal cyst

34
Q
A

spermatocele

35
Q
A

ectasia rete testis

36
Q
A

epididymal cyst

37
Q

testicular pain needs to be taken seriously due to the possibility of what

A

torsion

38
Q

2 main mesonephric (Wolffian) duct remnants

A

epididymal appendix
paradidymis

39
Q

main paramesonephric duct remnant (Mullerian)

A

testicular appendix

40
Q

irritation and swelling of epididymis due to bacterial infection

A

epididymitis

41
Q

Seminiferous tubules
Rete testes
derived from:

A

peritoneum

42
Q

seminal vesicle
ejaculatory duct
epididymis
appendix epididymis
tubules
vas deferens
efferent ductules

derived from:

A

mesonephric duct

43
Q

appendix testis
prostatic utricle

derived from:

A

paramesonephric duct

44
Q

shortens and drags testes into scrotum so sperm can function better at lower temp.

A

Gubernaculum

45
Q

descends in the normal path but does not reach scrotum

A

Cryptorchid testis

46
Q

descends in the normal path to the superficial inguinal ring, then tracks to other sites within the superficial fascia

A

Ectopic testis

47
Q

surgery for cryptorchid or ectopic testis

A

Orchiopexy

48
Q

in normal descent of testes, proximal portion of ______ undergoes apoptosis

A

vaginal process

49
Q

______ is on anterior aspect of testes

A

tunica vaginalis

50
Q

If the proximal portion of the Vaginal process does not undergo apoptosis, a large patency of the vaginal process is continuous with the peritoneal cavity.
Intestines may herniate into the scrotum.

A

congenital inguinal hernia

51
Q

A small patency of the vaginal process.
This results in a fluid filled cyst in the anterior scrotum.

A

hydrocele of testes

52
Q

fluid in tunica vaginalis of testes

A

hydrocele

53
Q

______ septum from mesoderm origin splits cloaca

A

urorectal septum

54
Q

3 parts of external genitalia formation

A

genital tubercle
genital folds
genital swellings

55
Q

elongates to form the shaft and glans penis

A

genital tubercle

56
Q

comes together to enclose the open ventral surface of the spongy/penile urethra

A

genital folds; urethral fold

57
Q

comes together to form
the scrotum

A

genital swellings/Labioscrotal swellings

58
Q

___ and ___ form shaft

A

crus and bulb of penis

59
Q

ventral side of penis

A

corpus spongiosum

60
Q

dorsal side of penis

A

corpus cavernosum

61
Q

failure of the genital folds to fuse ventrally

A

hypospadius

62
Q

ventral bending

A

chordee

63
Q

failure of the dorsal mesenchyme of the shaft (genital tubercle) to properly fuse

A

epispadius

64
Q

testosterone into DHT by what

A

5alpha-reductase

65
Q

4 main things that DHT helps form

A

penis
scrotum
prostate
bulbourethral glands

66
Q

treatment for boys with anomalies of male genitalia

A

testosterone

67
Q

treatment for male adults for anomalies of male genitalia

A

hCG

68
Q

Androgen is responsible for development of external structures
XY- male

Infertile

Testosterone not getting into cells and being converted to DHT
to develop external genitalia

A

Androgen Insensitivity syndrome

69
Q

Reifenstein Syndrome
Partial Androgen Insensitivity

46 XY; absence of sex chromatin in nuclei; varying degree of
development to internal and external genitalia; inadequate
production of testosterone and mullerian inhibiting factor

A

male pseudohermaphoditism

70
Q

structures derived from ______ duct are sensitive to testosterone

A

Mesonephric (Wolffian)

71
Q

structures derived from _____ and _____ sensitive to DHT

A

endoderm and mesoderm

ENR Biweekly 1 (11 decks)

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