Fields- formation of female reproductive system Flashcards
germ cells develop in ______ and migrate to genital ridge to develop into gametes
yolk sac
____ can develop into germ cell tumors
germ cells
+ LDH and +AFP; endoderm, mesoderm, ectoderm
Teratoma
+AFP and bhCG
embryonal carcinoma
+AFP
Yolk Sac tumor
+bhCG
choriocarcinoma
+LDH, AFP, bhCG (testis)
most common testicular cancer
seminoma
+LDH, AFP, bhCG (ovaries)
Dysgerminoma
+AFP, bhCG (extragonadal)
germinoma
weeks 1-6
intermediate mesoderm into indifferent gonad
how indifferent gonad turns into testis
Sry gene product (TDF) forms testis and inhibits Dax-1 on x chromosome
how indifferent gonads form ovaries in females
Dax-1 gene is responsible
peritoneum derived/sex cord derived structures in ovaries
follicle/granulosa cells
coelomic epithelium
fibroblast cell derived structure in ovary
theca cells (luteal cells)
how ovaries descend
gubernaculum
paramesonephric duct
Mullerian duct
mesonephric duct
Wolffian duct
remnants of mesonephric/Wolffian duct in female
cysts (gartner’s cyst)
structures of paramesonephric ducts in female
uterus
uterine tube
fimbria
cervix
upper 2/3rd of vagina
UG sinus in female
lower 1/3rd of vagina, vulva, urethra
UG sinus in male
bladder, prostate, urethra
paramesonephric duct body folding and fuse with uterus and uterine tube
uterus development
failure of paramesonephric duct to fuse
uterine anomalies
uterus didelphys
septate uterus and cervix; one vagina
typically associated with ectopic/undescended ovary
Unicornuate uterus
atresia of cervix
first stage of vagina development
second stage of vagina development
3rd stage of vagina development
paramesonephric ducts and sinovaginal bulbs fail to fuse: (2 vaginal openings)
bicollis
paramesonephric ducts fail to fuse and partial fusion of sinovaginal bulbs: Septated cervix and a partial vaginal septum with one vaginal opening
unicollis
failure to recanalize or imperforate hymen
imperforate vagina
retained menstrual blood in the uterus
Cyclic pelvic or abdominal pain with retention of urine in the bladder.
Endometrial cells in the menstrual fluid can retrograde to the uterine tube and then the pouch of Douglas causing endometriosis (hyperplasia and hypertrophy of endometrial cells that take up residence in the peritoneum.
Hematocolpos
_____ stimulated by parasympathetics
Greater vestibular glands
_____ stimulated by sympathetics
Skene’s glands (paraurethral glands)
_____ splits cloaca
urorectal septum
genital tubercle
genital fold
genital swelling
what germ layer
mesoderm
genital tubercle forms what 2 structures in female
clitoris and bulbs of vestibule
____ do not fuse like the male bulb of penis
bulbs of vestibule
genital fold/urethral fold form what structure in the female
labia minora
____ dont have fusion in females like they do in males
genital fold
labia minora homologous structure in males
skin of penis
labia majora homologous structure in males
scrotum
genital swelling forms what structure in females
labia majora
____ doesnt fuse in female like it does with the male scrotum
genital swelling
structures formed from genital tubercle in female
clitoris
bulbs of vestibule
crura
body of clitoris
corpus cavernosum
bulbs of vestibule forms
corpus spongiosum
attached portions of body of clitoris
crura
skeletal muscle that covers the clitoris and bulbs of vestibule derived from what
paraxial mesoderm