FEN

Question 1

Vitamin D physiology

Answer 1

UV light turns 7-Dehydrocholesterol in epidermis to D3 and D3 intake are cholecalciferol, D2 intake is Ergocalciferol —–Liver converts to 25-OH vitamin D (calcidiol)——Kidney converts to 1-25 Dihydroxyvitamin D. (calcitriol)

this helps strengthen bones, increase GI tract absorb Calcium, and Phos

Question 2

difference between 25-OH vitamin D and 1-25 DiOH Vitamin D?

Answer 2

25 hydroxyvitamin D is 1% as potent as 1-25 Dihydroxyvitamin D.

Question 3

What happens to homocysteine if there is a B12 def?

Answer 3

Homocysteine needs B12 to be converted into methionine. Therefore it raises.

Question 4

What is the name for Vitamin B12, and vitamin B9

Answer 4

Cobalamin, Folate

Question 5

Good confirmatory markers for B12 status.

Answer 5

Methylmalonic acid above 0.271 micromol/L or Homocysteine level above 15 micromol/L

Question 6

what Def can cause elevated homocysteine but not Methylmalonic acid?

Answer 6

Folate and B12 def can cause elevated homocysteine but only B12 def can cause methylmalonic acid to rise.

Question 7

Potential danger of elevated B12 levels and folate

Answer 7

Possible risk of developing Cancer goes up when over 800 and the risk of not recovering from cancer goes up as well.

Question 8

treatment options for Hypercalcemia?

Answer 8

IV fluids, Calcitonin, Bisphosphonates, Loop Diuretics (not in cancer)

Question 9

RDA for calcium and Vit D3

Answer 9

Calcium 1-3 y 700, 4-8 1000, 9-18 1300,
Vit D3 1-18 600 IU,

Question 10

Conversion of IU to MCG

Answer 10

1 IU = 0.025 mcg of Vit D
600 IU = 15 mcg Vit D

Question 11

How does Vit D levels impact Calcium absorption

Answer 11

If Vit D is adequate >35, Calcium 30-40% absorbed, If Vit D is inadequate Calcium is only 10-15%