Female Reproductive System Flashcards
The two major functions of the ovaries are _____ (estrogen and progesterone production) and _______ (oocytes and ova production)
steroidogenesis
gametogenesis
The ovarian capsule (_____ _____) is a layer of dense irregular connective tissue
tunica albuginea
The ovaries are covered by a simple cuboidal or squamos epithelium known as the _____ epithelium
germinal
The ovarian _____ contains ovarian follicles
cortex
The ovarian _____ contains large blood vessels, lymphatic vessels, and nerves in a loose CT stroma
medulla
The three types of ovarian follicles are ___ ____ and _____
primordial
growing
graafian
The primordial follicle is a ____ ____ covered by 1 layer of squamous follicular cells
primary oocyte
The key feature of an oocyte is presence of many golgi regions, mitochondria, and rER profiles, all together forming a _____ ____
balbiani body
Oocytes are arrested in _____ of meiosis 1 and may remain in this stage for many years
prophase
Primordial follicles have a large, acentric ____
nucleus
___ cells are separated from stroma by a basal lamina and attach to each other by desmosomes
follicular
What is the growing cycle of an oocyte? Primordial follicle –>
primordial–>primary–>multilamellar–>secondary–>graafian
The three kinds of growing follicles are : ____, ___, and _____
primary
multilamellar
secondary
Primary follicles have an amorphous layer called ___ ____ that is acidophillic and surrounds the oocyte
zona pellucida
Primary _____ follicles develop from primordial follicles and have 1 layer of _____ follicular cells surrounding the oocyte
unilaminar
cuboidal
____ primary follicles develop from unilaminar folicles by proliferation of ____ cells
multilaminar
follicular
Multilaminar follicles have several layers of follicular cells called ____ cells
granulosa
Stromal cells form a sheath around granulosa cells called the ____ ____ in multilaminar cells
theca folliculi
The theca folliculi is divided into an inner cellular cuboidal layer called _____ ____ and an outer fibrous layer called ___ ____
theca interna
theca externa
Secondary (___) follicles are established when fluid (liquor folliculi) accumulates in intercellular spaces between granulosa cells
antral
The liquor folliculi fills intercellular spaces and coalesces, forming a single large cavity called the _____
antrum
____ stimulates granulosa cells to convert androgens made by theca interna cells into estrogens and to manufacture membrane receptors of _____ hormone
FSH
lutenizing
____ from the oocyte and narrow processes from the granulosa cells extend into the zona pellucida
microvilli
____ cells contact each other via gap junctions and form ga junctions with the oocyte plasma membrane
granulosa
The theca ____ makes androgens, which are transferred to ____ cells and converted into estrogens
interna
granulosa
The _____ (mature) follicle is the one follicle among secondary follicles that will ovulate
graafian
The graafian follicle has an ____ positioned oocyte located on a small mound of granulosa cells called the _____ ____, which projects into the antrum
acentrically
cumulus oophorus
The ____ ____ is mainly collagenous and contains many blood vessels which nourish the theca interna
theca externa
The primary oocyte completes its first meiotic division just prior to ovulation, forming a ____ ____ and the first ___ ____
secondary oocyte
polar body
After its first meiotic division, the secondary oocyte beings its second meiotic division but is blocked at ____. When the sperm contacts the secondary oocyte, a reaction with _____ enzymes initiates the second meiotic division
metaphase
acrosomal
Sperm fertilizes the ___ ovum that results from the second meiotic division
haploid
Acrosomal reaction causes the ___ ____ on the oocyte to breakdown so that other sperm cannot attach
zona pellucida
Ovulation occurs in response to a surge of _____ as the secondary oocyte and the cumulus cells (____ ____) leave the ruptured follicle to enter the fimbriated oviduct end
LH
Corona radiata
The ____ ____ is made of granulosa lutein cells and theca lutein cells
corpus luteum
The corpus luteum is a temporary ____ gland, whose formation depends on LH
endocrine
Granulosa lutein cells are large, pale, and have abundant sER and rER. They manufacture most of the body’s _______ and convert androgens from theca lutein cells into _____
progesterone
estradiol
Theca lutein cells are small and concentrated mainly on the corpus luteum _____. They manufacture _____ and small amounts of estrogen and progesteone
periphery
androstenedione
The ____ ____ is a small scar formed from the corpus luteum remnants after function ceases and it degenerates
corpus albicans
____ follicles are those that are undergoing degneration
atretitc
Atretic follicles are commonly present in the ovary; after a graafian follicle ovulates, the remaining _____ Follicles degenerate
secondary
Oviducts/fallopian tubes have a wall consisting of ___ ____ and ____
mucosa, muscularis, serosa
Fallopian tubes are divided into 4 regions: ____, ____, ____, and ____
infidibulum
ampulla
isthmus
intramural piortion
The mucosa of the oviduct has extensive ____ folds in the infindibulum
longitudinal